CYP26B1 Antikörper (Internal Region)

Produktnummer ABIN6261169

Produktdetails anti-CYP26B1 Antikörper

Target: CYP26B1 (Cytochrome P450, Family 26, Subfamily B, Polypeptide 1 (CYP26B1))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CYP26B1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: CYP26B1 Antibody detects endogenous levels of total CYP26B1.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CYP26B1, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu CYP26B1

Target: CYP26B1 (Cytochrome P450, Family 26, Subfamily B, Polypeptide 1 (CYP26B1))

Andere Bezeichnung: CYP26B1 (CYP26B1 Produkte)

Synonyme: cyp26b1 antikoerper, cyp26a2 antikoerper, p450rai-2 antikoerper, CYP26A2 antikoerper, P450RAI-2 antikoerper, P450RAI2 antikoerper, RHFCA antikoerper, CP26 antikoerper, fc21d03 antikoerper, wu:fc21d03 antikoerper, wu:fc26h10 antikoerper, zgc:76999 antikoerper, cytochrome P450 26B1 antikoerper, cytochrome P450 family 26 subfamily B member 1 L homeolog antikoerper, cytochrome P450 family 26 subfamily B member 1 antikoerper, cytochrome P450, family 26, subfamily B, polypeptide 1 antikoerper, cytochrome P450, family 26, subfamily b, polypeptide 1 antikoerper, CpipJ_CPIJ002537 antikoerper, cyp26b1.L antikoerper, CYP26B1 antikoerper, cyp26b1 antikoerper, Cyp26b1 antikoerper

Hintergrund:

Description: Involved in the metabolism of retinoic acid (RA), rendering this classical morphogen inactive through oxidation. Involved in the specific inactivation of all-trans-retinoic acid (all-trans-RA), with a preference for the following substrates: all-trans-RA > 9-cis-RA > 13-cis-RA. Generates several hydroxylated forms of RA, including 4-OH-RA, 4-oxo-RA, and 18-OH-RA. Essential for postnatal survival. Plays a central role in germ cell development: acts by degrading RA in the developing testis, preventing STRA8 expression, thereby leading to delay of meiosis. Required for the maintenance of the undifferentiated state of male germ cells during embryonic development in Sertoli cells, inducing arrest in G0 phase of the cell cycle and preventing meiotic entry. Plays a role in skeletal development, both at the level of patterning and in the ossification of bone and the establishment of some synovial joints.

Gene: CYP26B1

Molekulargewicht: 58-60 kDa

Gen-ID: 56603

UniProt: Q9NR63

Pathways: Retinoic Acid Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation, Monocarboxylic Acid Catabolic Process