CIDEC Antikörper (Internal Region)

Produktnummer ABIN6260841

Produktdetails anti-CIDEC Antikörper

Target: CIDEC (Cell Death-Inducing DFFA-Like Effector C (CIDEC))

Bindungsspezifität: Internal Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CIDEC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Spezifität: CIDEC Antibody detects endogenous levels of total CIDEC.

Homologie: Horse

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CIDEC, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu CIDEC

Target: CIDEC (Cell Death-Inducing DFFA-Like Effector C (CIDEC))

Andere Bezeichnung: CIDEC (CIDEC Produkte)

Synonyme: fsp27 antikoerper, cide-3 antikoerper, MGC89274 antikoerper, cidec antikoerper, MGC82483 antikoerper, CIDEC antikoerper, fd36c01 antikoerper, wu:fd36c01 antikoerper, zgc:153033 antikoerper, CIDE-3 antikoerper, CIDE3 antikoerper, FPLD5 antikoerper, FSP27 antikoerper, Fsp27 antikoerper, CIDE-C antikoerper, cell death inducing DFFA like effector c antikoerper, cell death inducing DFFA like effector c S homeolog antikoerper, cell death-inducing DFFA-like effector c antikoerper, Cell death activator CIDE-3 antikoerper, cidec antikoerper, cidec.S antikoerper, CIDEC antikoerper, Cidec antikoerper

Hintergrund:

Description: Binds to lipid droplets and regulates their enlargement, thereby restricting lipolysis and favoring storage. At focal contact sites between lipid droplets, promotes directional net neutral lipid transfer from the smaller to larger lipid droplets. The transfer direction may be driven by the internal pressure difference between the contacting lipid droplet pair. Its role in neutral lipid transfer and lipid droplet enlargement is activated by the interaction with PLIN1. May act as a CEBPB coactivator in the white adipose tissue to control the expression of a subset of CEBPB downstream target genes, including SOCS1, SOCS3, TGFB1, TGFBR1, ID2 and XDH. When overexpressed in preadipocytes, induces apoptosis or increases cell susceptibility to apoptosis induced by serum deprivation or TGFB treatment. As mature adipocytes, that express high CIDEC levels, are quite resistant to apoptotic stimuli, the physiological significance of its role in apoptosis is unclear. May play a role in the modulation of the response to osmotic stress by preventing NFAT5 to translocate into the nucleus and activate its target genes expression.

Gene: CIDEC

Molekulargewicht: 26 kDa

Gen-ID: 63924

UniProt: Q96AQ7