CCRN4L Antikörper

Produktnummer ABIN6260565

Produktdetails anti-CCRN4L Antikörper

Target: CCRN4L (CCR4 Carbon Catabolite Repression 4-Like (CCRN4L))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCRN4L Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: CCRN4L Antibody detects endogenous levels of total CCRN4L

Kreuzreaktivität: Human, Maus, Ratte (Rattus)

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CCRN4L

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C.Stable for 12 months from date of receipt

Haltbarkeit: 12 months

Details zu CCRN4L

Target: CCRN4L (CCR4 Carbon Catabolite Repression 4-Like (CCRN4L))

Andere Bezeichnung: CCRN4L (CCRN4L Produkte)

Synonyme: CCR4L antikoerper, NOC antikoerper, AU043840 antikoerper, Ccr4 antikoerper, nocturnin antikoerper, Ccrn4lb antikoerper, MNOC antikoerper, ccr4l antikoerper, noc antikoerper, MGC85016 antikoerper, ccrn4l antikoerper, CCRN4L antikoerper, nocturnin antikoerper, nocturnin S homeolog antikoerper, nocturnin L homeolog antikoerper, putative nocturnin antikoerper, NOCT antikoerper, Noct antikoerper, noct antikoerper, noct.S antikoerper, noct.L antikoerper, LOC5570471 antikoerper, CpipJ_CPIJ011434 antikoerper, Smp_105040 antikoerper

Hintergrund:

Description: Circadian deadenylase which plays an important role in post-transcriptional regulation of metabolic genes under circadian control. Degrades poly(A) tails of specific target mRNAs leading to their degradation and suppression of translation. Exerts a rhythmic post-transcriptional control of genes necessary for metabolic functions including nutrient absorption, glucose/insulin sensitivity, lipid metabolism, adipogenesis, inflammation and osteogenesis. Plays an important role in favoring adipogenesis over osteoblastogenesis and acts as a key regulator of the adipogenesis/osteogenesis balance. Promotes adipogenesis by activating PPARG transcriptional activity in a deadenylase-independent manner by facilitating its nuclear translocation. Regulates circadian expression of NOS2 in the liver and negatively regulates the circadian expression of IGF1 in the bone. Critical for proper development of early embryos (By similarity).

Gene: NOCT

Molekulargewicht: 48 kDa

Gen-ID: 25819

UniProt: Q9UK39

Pathways: Ribonucleoprotein Complex Subunit Organization