CCR2 Antikörper (Internal Region)
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- Target Alle CCR2 Antikörper anzeigen
- CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))
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Bindungsspezifität
- Internal Region
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CCR2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- CCR2 Antibody detects endogenous levels of total CCR2.
- Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human CCR2, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product CCR2 Primärantikörper
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- Applikationshinweise
- WB 1:1000-3000, IHC 1:200, IF/ICC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))
- Andere Bezeichnung
- CCR2 (CCR2 Produkte)
- Synonyme
- CC-CKR-2 antikoerper, CCR-2 antikoerper, CCR2A antikoerper, CCR2B antikoerper, CD192 antikoerper, CKR2 antikoerper, CKR2A antikoerper, CKR2B antikoerper, CMKBR2 antikoerper, MCP-1-R antikoerper, ACKR5 antikoerper, CKRX antikoerper, CRAM antikoerper, CRAM-A antikoerper, CRAM-B antikoerper, HCR antikoerper, Cc-ckr-2 antikoerper, Ccr2a antikoerper, Ccr2b antikoerper, Ckr2 antikoerper, Ckr2a antikoerper, Ckr2b antikoerper, Cmkbr2 antikoerper, mJe-r antikoerper, C-C motif chemokine receptor 2 antikoerper, C-C motif chemokine receptor like 2 antikoerper, chemokine (C-C motif) receptor 2 antikoerper, CCR2 antikoerper, CCRL2 antikoerper, Ccr2 antikoerper, LOC484790 antikoerper
- Hintergrund
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Description: Receptor for the CCL2, CCL7 and CCL13 chemokines (PubMed:23408426). Receptor for the beta-defensin DEFB106A/DEFB106B (PubMed:23938203). Transduces a signal by increasing intracellular calcium ion levels (By similarity). Upon CCL2 ligation, mediates chemotaxis and migration induction through the activation of the PI3K cascade, the small G protein Rac and lamellipodium protrusion (Probable).
Gene: CCR2
- Molekulargewicht
- 42 kDa
- Gen-ID
- 729230
- UniProt
- P41597
- Pathways
- cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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