CBX2 Antikörper (Internal Region)
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- Target Alle CBX2 Antikörper anzeigen
- CBX2 (Chromobox Homolog 2 (CBX2))
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Bindungsspezifität
- Internal Region
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CBX2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Spezifität
- CBX2 Antibody detects endogenous levels of total CBX2.
- Homologie
- Pig,Bovine,Sheep,Rabbit
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human CBX2, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product CBX2 Primärantikörper
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- Applikationshinweise
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- CBX2 (Chromobox Homolog 2 (CBX2))
- Andere Bezeichnung
- CBX2 (CBX2 Produkte)
- Synonyme
- cbx2 antikoerper, M33 antikoerper, pc1 antikoerper, wu:fd20e09 antikoerper, zgc:103563 antikoerper, MOD2 antikoerper, pc antikoerper, CDCA6 antikoerper, SRXY5 antikoerper, cdca6 antikoerper, m33 antikoerper, chromobox 2 antikoerper, chromobox homolog 2 (Drosophila Pc class) antikoerper, chromobox 2 L homeolog antikoerper, cbx2 antikoerper, CBX2 antikoerper, Cbx2 antikoerper, cbx2.L antikoerper
- Hintergrund
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Description: Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development (PubMed:21282530). PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility (PubMed:21282530). Binds to histone H3 trimethylated at 'Lys-9' (H3K9me3) or at 'Lys-27' (H3K27me3) (By similarity). Plays a role in the lineage differentiation of the germ layers in embryonic development (By similarity). Involved in sexual development, acting as activator of NR5A1 expression (PubMed:19361780).
Gene: CBX2
- Molekulargewicht
- 56 kDa
- Gen-ID
- 84733
- UniProt
- Q14781
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