ATP6AP1 Antikörper (Internal Region)

Produktnummer ABIN6260131

Produktdetails anti-ATP6AP1 Antikörper

Target: ATP6AP1 (ATPase, H+ Transporting, Lysosomal Accessory Protein 1 (ATP6AP1))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATP6AP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: ATP6AP1 Antibody detects endogenous levels of total ATP6AP1.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human ATP6AP1, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu ATP6AP1

Target: ATP6AP1 (ATPase, H+ Transporting, Lysosomal Accessory Protein 1 (ATP6AP1))

Andere Bezeichnung: ATP6AP1 (ATP6AP1 Produkte)

Synonyme: 16A antikoerper, ATP6IP1 antikoerper, ATP6S1 antikoerper, Ac45 antikoerper, CF2 antikoerper, VATPS1 antikoerper, XAP-3 antikoerper, XAP3 antikoerper, AC45 antikoerper, AI316502 antikoerper, AW108110 antikoerper, Atp6ip1 antikoerper, Atp6s1 antikoerper, C7-1 antikoerper, mFLJ00383 antikoerper, H+-ATPase antikoerper, ATPase H+ transporting accessory protein 1 antikoerper, ATPase, H+ transporting, lysosomal accessory protein 1 antikoerper, plasma membrane ATPase 4 antikoerper, ATP6AP1 antikoerper, Atp6ap1 antikoerper, LOC547525 antikoerper

Hintergrund:

Description: Accessory subunit of the proton-transporting vacuolar (V)-ATPase protein pump, which is required for luminal acidification of secretory vesicles. Guides the V-type ATPase into specialized subcellular compartments, such as neuroendocrine regulated secretory vesicles or the ruffled border of the osteoclast, thereby regulating its activity. Involved in membrane trafficking and Ca2+-dependent membrane fusion. May play a role in the assembly of the V-type ATPase complex. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe2+ prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation (PubMed:28296633).

Gene: ATP6AP1

Molekulargewicht: 52kDa

Gen-ID: 537

UniProt: Q15904

Pathways: Proton Transport, SARS-CoV-2 Protein Interaktom