APLP1 Antikörper (Internal Region)

Produktnummer ABIN6259980

Produktdetails anti-APLP1 Antikörper

Target: APLP1 (Amyloid beta (A4) Precursor-Like Protein 1 (APLP1))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser APLP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Spezifität: APLP1 Antibody detects endogenous levels of total APLP1.

Homologie: Pig,Bovine,Horse,Sheep,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human APLP1, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:100, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu APLP1

Target: APLP1 (Amyloid beta (A4) Precursor-Like Protein 1 (APLP1))

Andere Bezeichnung: APLP1 (APLP1 Produkte)

Synonyme: aplp antikoerper, MGC115336 antikoerper, APLP antikoerper, Aplp1_retired antikoerper, RGD1561211 antikoerper, amyloid beta precursor like protein 1 antikoerper, amyloid beta precursor like protein 1 L homeolog antikoerper, amyloid beta (A4) precursor-like protein 1 antikoerper, APLP1 antikoerper, aplp1.L antikoerper, aplp1 antikoerper, Aplp1 antikoerper

Hintergrund:

Description: May play a role in postsynaptic function. The C-terminal gamma-secretase processed fragment, ALID1, activates transcription activation through APBB1 (Fe65) binding (By similarity). Couples to JIP signal transduction through C-terminal binding. May interact with cellular G-protein signaling pathways. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I.

Gene: APLP1

Molekulargewicht: 72kD

Gen-ID: 333

UniProt: P51693

Pathways: cAMP Metabolic Process