Antizyme Inhibitor 1 Antikörper (Internal Region)
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- Target Alle Antizyme Inhibitor 1 (AZIN1) Antikörper anzeigen
- Antizyme Inhibitor 1 (AZIN1)
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Bindungsspezifität
- Internal Region
- Reaktivität
- Human, Ratte, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Antizyme Inhibitor 1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Spezifität
- Antizyme inhibitor 1 Antibody detects endogenous levels of total Antizyme inhibitor 1.
- Homologie
- Pig,Bovine,Sheep,Rabbit,Dog,Chicken,Xenopus
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human Antizyme inhibitor 1, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product AZIN1 Primärantikörper
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- Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- Antizyme Inhibitor 1 (AZIN1)
- Andere Bezeichnung
- AZIN1 (AZIN1 Produkte)
- Synonyme
- OAZI antikoerper, OAZIN antikoerper, ODC1L antikoerper, 1700085L02Rik antikoerper, AI414949 antikoerper, Oazi antikoerper, Oazin antikoerper, AZIN1 antikoerper, azin1 antikoerper, oazin antikoerper, wu:fj32d12 antikoerper, MGC81852 antikoerper, wu:fc93f10 antikoerper, zgc:110131 antikoerper, antizyme inhibitor 1 antikoerper, antizyme inhibitor 1b antikoerper, antizyme inhibitor 1 L homeolog antikoerper, antizyme inhibitor 1a antikoerper, AZIN1 antikoerper, Azin1 antikoerper, azin1b antikoerper, azin1.L antikoerper, azin1 antikoerper, azin1a antikoerper
- Hintergrund
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Description: Antizyme inhibitor (AZI) protein that positively regulates ornithine decarboxylase (ODC) activity and polyamine uptake. AZI is an enzymatically inactive ODC homolog that counteracts the negative effect of ODC antizymes (AZs) OAZ1, OAZ2 and OAZ3 on ODC activity by competing with ODC for antizyme-binding (PubMed:17900240, PubMed:26305948). Inhibits antizyme-dependent ODC degradation and releases ODC monomers from their inactive complex with antizymes, leading to formation of the catalytically active ODC homodimer and restoring polyamine production (PubMed:17900240).
Gene: AZIN1
- Molekulargewicht
- 49.5 kDa
- Gen-ID
- 51582
- UniProt
- O14977
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