Antizyme Inhibitor 1 Antikörper (Internal Region)

Produktnummer ABIN6259946

Produktdetails anti-Antizyme Inhibitor 1 Antikörper

Target: Antizyme Inhibitor 1 (AZIN1)

Bindungsspezifität: Internal Region

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Antizyme Inhibitor 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Spezifität: Antizyme inhibitor 1 Antibody detects endogenous levels of total Antizyme inhibitor 1.

Homologie: Pig,Bovine,Sheep,Rabbit,Dog,Chicken,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Antizyme inhibitor 1, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu Antizyme Inhibitor 1

Target: Antizyme Inhibitor 1 (AZIN1)

Andere Bezeichnung: AZIN1 (AZIN1 Produkte)

Synonyme: OAZI antikoerper, OAZIN antikoerper, ODC1L antikoerper, 1700085L02Rik antikoerper, AI414949 antikoerper, Oazi antikoerper, Oazin antikoerper, AZIN1 antikoerper, azin1 antikoerper, oazin antikoerper, wu:fj32d12 antikoerper, MGC81852 antikoerper, wu:fc93f10 antikoerper, zgc:110131 antikoerper, antizyme inhibitor 1 antikoerper, antizyme inhibitor 1b antikoerper, antizyme inhibitor 1 L homeolog antikoerper, antizyme inhibitor 1a antikoerper, AZIN1 antikoerper, Azin1 antikoerper, azin1b antikoerper, azin1.L antikoerper, azin1 antikoerper, azin1a antikoerper

Hintergrund:

Description: Antizyme inhibitor (AZI) protein that positively regulates ornithine decarboxylase (ODC) activity and polyamine uptake. AZI is an enzymatically inactive ODC homolog that counteracts the negative effect of ODC antizymes (AZs) OAZ1, OAZ2 and OAZ3 on ODC activity by competing with ODC for antizyme-binding (PubMed:17900240, PubMed:26305948). Inhibits antizyme-dependent ODC degradation and releases ODC monomers from their inactive complex with antizymes, leading to formation of the catalytically active ODC homodimer and restoring polyamine production (PubMed:17900240).

Gene: AZIN1

Molekulargewicht: 49.5 kDa

Gen-ID: 51582

UniProt: O14977