ANG Antikörper (Internal Region)

Produktnummer ABIN6259924

Produktdetails anti-ANG Antikörper

Target: ANG (Angiogenin (ANG))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ANG Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Spezifität: Angiogenin Antibody detects endogenous levels of total Angiogenin.

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Angiogenin, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu ANG

Target: ANG (Angiogenin (ANG))

Andere Bezeichnung: ANG (ANG Produkte)

Synonyme: ALS9 antikoerper, HEL168 antikoerper, RNASE4 antikoerper, RNASE5 antikoerper, ANG antikoerper, AI385586 antikoerper, Ang1 antikoerper, Rnase5 antikoerper, Rnase5a antikoerper, ANG1 antikoerper, angiogenin antikoerper, angiogenin, ribonuclease, RNase A family, 5 antikoerper, ribonuclease A family member k6 antikoerper, ANG antikoerper, Ang antikoerper, RNASE6 antikoerper

Hintergrund:

Description: Binds to actin on the surface of endothelial cells, once bound, angiogenin is endocytosed and translocated to the nucleus. Stimulates ribosomal RNA synthesis including that containing the initiation site sequences of 45S rRNA. Cleaves tRNA within anticodon loops to produce tRNA-derived stress-induced fragments (tiRNAs) which inhibit protein synthesis and triggers the assembly of stress granules (SGs). Angiogenin induces vascularization of normal and malignant tissues. Angiogenic activity is regulated by interaction with RNH1 in vivo.

Gene: ANG

Molekulargewicht: 17kDa

Gen-ID: 283

UniProt: P03950