TOPORS Antikörper (C-Term)

Produktnummer ABIN6259220

Produktdetails anti-TOPORS Antikörper

Target: TOPORS (Topoisomerase I Binding, arginine/serine-Rich, E3 Ubiquitin Protein Ligase (TOPORS))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TOPORS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Spezifität: TOPRS Antibody detects endogenous levels of total TOPRS.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human TOPRS, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu TOPORS

Target: TOPORS (Topoisomerase I Binding, arginine/serine-Rich, E3 Ubiquitin Protein Ligase (TOPORS))

Andere Bezeichnung: TOPORS (TOPORS Produkte)

Synonyme: CG15104 antikoerper, Dmel\\CG15104 antikoerper, TOPORS antikoerper, dTopors antikoerper, dtopors antikoerper, fi75f04 antikoerper, wu:fi75f04 antikoerper, AW105885 antikoerper, LUN antikoerper, TP53BPL antikoerper, p53BP3/LUN antikoerper, P53BP3 antikoerper, RP31 antikoerper, Topoisomerase I-interacting protein antikoerper, TOP1 binding arginine/serine rich protein antikoerper, topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase antikoerper, topoisomerase I binding, arginine/serine-rich b antikoerper, topoisomerase I binding, arginine/serine-rich antikoerper, Topors antikoerper, TOPORS antikoerper, topors antikoerper, toporsb antikoerper

Hintergrund:

Description: Functions as an E3 ubiquitin-protein ligase and as an E3 SUMO1-protein ligase. Probable tumor suppressor involved in cell growth, cell proliferation and apoptosis that regulates p53/TP53 stability through ubiquitin-dependent degradation. May regulate chromatin modification through sumoylation of several chromatin modification-associated proteins. May be involved in DNA damage-induced cell death through IKBKE sumoylation.

Gene: TOPORS

Gen-ID: 10210

UniProt: Q9NS56

Pathways: Maintenance of Protein Location