RRAGB Antikörper (Internal Region)

Produktnummer ABIN6259180

Produktdetails anti-RRAGB Antikörper

Target: RRAGB (Ras-Related GTP Binding B (RRAGB))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RRAGB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: RRAGB Antibody detects endogenous levels of total RRAGB.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human RRAGB, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu RRAGB

Target: RRAGB (Ras-Related GTP Binding B (RRAGB))

Andere Bezeichnung: RRAGB (RRAGB Produkte)

Synonyme: RAGB antikoerper, bA465E19.1 antikoerper, Ragb antikoerper, RRAGB antikoerper, Ras related GTP binding B antikoerper, Ras-related GTP binding B antikoerper, RRAGB antikoerper, RragB antikoerper, Rragb antikoerper

Hintergrund:

Description: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade. Forms heterodimeric Rag complexes with RRAGC or RRAGD and cycles between an inactive GDP-bound and an active GTP-bound form. In its active form participates in the relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. Involved in the RCC1/Ran-GTPase pathway.

Gene: RRAGB

Molekulargewicht: 43 kDa

Gen-ID: 10325

UniProt: Q5VZM2