KCNE2 Antikörper (Internal Region)

Produktnummer ABIN6258938

Produktdetails anti-KCNE2 Antikörper

Target: KCNE2 (Potassium Voltage-Gated Channel, Isk-Related Family, Member 2 (KCNE2))

Bindungsspezifität: Internal Region

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KCNE2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Spezifität: KCNE2 Antibody detects endogenous levels of total KCNE2.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human KCNE2, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu KCNE2

Target: KCNE2 (Potassium Voltage-Gated Channel, Isk-Related Family, Member 2 (KCNE2))

Andere Bezeichnung: KCNE2 (KCNE2 Produkte)

Synonyme: ATFB4 antikoerper, LQT5 antikoerper, LQT6 antikoerper, MIRP1 antikoerper, Mirp1 antikoerper, MiRP1 antikoerper, 2200002I16Rik antikoerper, AW048273 antikoerper, potassium voltage-gated channel subfamily E regulatory subunit 2 antikoerper, potassium voltage-gated channel, Isk-related subfamily, gene 2 antikoerper, KCNE2 antikoerper, Kcne2 antikoerper

Hintergrund:

Description: Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1. Associated with KCNH2/HERG is proposed to form the rapidly activating component of the delayed rectifying potassium current in heart (IKr). May associate with KCNQ2 and/or KCNQ3 and modulate the native M-type current. May associate with HCN1 and HCN2 and increase potassium current. Interacts with KCNQ1, forms a heterooligomer complex leading to currents with an apparently instantaneous activation, a rapid deactivation process and a linear current-voltage relationship and decreases the amplitude of the outward current (PubMed:11101505).

Gene: KCNE2

Molekulargewicht: ?14 kDa

Gen-ID: 9992

UniProt: Q9Y6J6