HSD3B7 Antikörper (Internal Region)
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- Target Alle HSD3B7 Antikörper anzeigen
- HSD3B7 (Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 7 (HSD3B7))
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Bindungsspezifität
- Internal Region
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser HSD3B7 Antikörper ist unkonjugiert
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Applikation
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- HSD3B7 Antibody detects endogenous levels of total HSD3B7.
- Homologie
- Pig,Bovine,Horse,Sheep,Dog,Chicken
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human HSD3B7, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product HSD3B7 Primärantikörper
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- Applikationshinweise
- WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- HSD3B7 (Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 7 (HSD3B7))
- Andere Bezeichnung
- HSD3B7 (HSD3B7 Produkte)
- Synonyme
- CBAS1 antikoerper, PFIC4 antikoerper, SDR11E3 antikoerper, AI195443 antikoerper, BB098564 antikoerper, Cca2 antikoerper, hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 antikoerper, HSD3B7 antikoerper, Hsd3b7 antikoerper
- Hintergrund
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Description: The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. HSD VII is active against four 7-alpha-hydroxylated sterols. Does not metabolize several different C(19/21) steroids as substrates. Involved in bile acid synthesis (PubMed:11067870). Plays a key role in cell positioning and movement in lymphoid tissues by mediating degradation of 7-alpha,25-dihydroxycholesterol (7-alpha,25-OHC): 7-alpha,25-OHC acts as a ligand for the G protein-coupled receptor GPR183/EBI2, a chemotactic receptor for a number of lymphoid cells.
Gene: HSD3B7
- Molekulargewicht
- 41 kDa
- Gen-ID
- 80270
- UniProt
- Q9H2F3
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