CD2AP Antikörper (Internal Region)
-
- Target Alle CD2AP (Cd2ap) Antikörper anzeigen
- CD2AP (Cd2ap) (CD2-Associated Protein (Cd2ap))
-
Bindungsspezifität
- Internal Region
- Reaktivität
- Human, Ratte, Maus
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser CD2AP Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
- Spezifität
- CD2AP Antibody detects endogenous levels of total CD2AP.
- Homologie
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human CD2AP, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product Cd2ap Primärantikörper
-
-
- Applikationshinweise
- WB 1:500-1:2000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Haltbarkeit
- 12 months
-
- Target
- CD2AP (Cd2ap) (CD2-Associated Protein (Cd2ap))
- Andere Bezeichnung
- CD2AP (Cd2ap Produkte)
- Synonyme
- cd2apl antikoerper, fj51c01 antikoerper, im:7153970 antikoerper, si:ch211-207n9.1 antikoerper, wu:fj51c01 antikoerper, zgc:103705 antikoerper, DKFZp469E061 antikoerper, CMS antikoerper, AL024079 antikoerper, C78928 antikoerper, METS-1 antikoerper, Mets1 antikoerper, CD2-associated protein L homeolog antikoerper, CD2 associated protein antikoerper, CD2-associated protein antikoerper, cd2ap.L antikoerper, CD2AP antikoerper, cd2ap antikoerper, Cd2ap antikoerper
- Hintergrund
-
Description: Seems to act as an adapter protein between membrane proteins and the actin cytoskeleton (PubMed:10339567). In collaboration with CBLC, modulates the rate of RET turnover and may act as regulatory checkpoint that limits the potency of GDNF on neuronal survival. Controls CBLC function, converting it from an inhibitor to a promoter of RET degradation (By similarity). May play a role in receptor clustering and cytoskeletal polarity in the junction between T-cell and antigen-presenting cell (By similarity). May anchor the podocyte slit diaphragm to the actin cytoskeleton in renal glomerolus. Also required for cytokinesis (PubMed:15800069). Plays a role in epithelial cell junctions formation (PubMed:22891260).
Gene: CD2AP
- Molekulargewicht
- 74 kDa
- Gen-ID
- 23607
- UniProt
- Q9Y5K6
-