VPS26B Antikörper (Internal Region)

Produktnummer ABIN6258353

Produktdetails anti-VPS26B Antikörper

Target: VPS26B (Vacuolar Protein Sorting 26 Homolog B (VPS26B))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VPS26B Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: VPS26B Antibody detects endogenous levels of total VPS26B.

Homologie: Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human VPS26B, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu VPS26B

Target: VPS26B (Vacuolar Protein Sorting 26 Homolog B (VPS26B))

Andere Bezeichnung: VPS26B (VPS26B Produkte)

Synonyme: VPS26B antikoerper, wu:fb49d07 antikoerper, wu:fb50d06 antikoerper, zgc:56297 antikoerper, pep8b antikoerper, vps26b antikoerper, Pep8b antikoerper, VP26B antikoerper, 1810012I05Rik antikoerper, 2310075A12Rik antikoerper, AI848392 antikoerper, T29A15.180 antikoerper, T29A15_180 antikoerper, vacuolar protein sorting 26B antikoerper, vacuolar protein sorting 26 homolog B (S. pombe) antikoerper, VPS26, retromer complex component B antikoerper, VPS26 retromer complex component B antikoerper, VPS26 retromer complex component B S homeolog antikoerper, vacuolar protein sorting 26B antikoerper, VPS26B antikoerper, vps26b antikoerper, vps26b.S antikoerper, Vps26b antikoerper

Hintergrund:

Description: Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. The recruitment of the CSC to the endosomal membrane involves RAB7A and SNX3. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX3-retromer mediates the retrograde transport of WLS distinct from the SNX-BAR retromer pathway. The SNX27-retromer is believed to be involved in endosome-to-plasma membrane trafficking and recycling of a broad spectrum of cargo proteins. The CSC seems to act as recruitment hub for other proteins, such as the WASH complex and TBC1D5. May be involved in retrograde transport of SORT1 but not of IGF2R. Acts redundantly with VSP26A in SNX-27 mediated endocytic recycling of SLC2A1/GLUT1 (By similarity).

Gene: VPS26B

Molekulargewicht: 45 kDa

Gen-ID: 112936

UniProt: Q4G0F5

Pathways: Cellular Glucan Metabolic Process