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GPR52 Antikörper (Internal Region)

GPR52 Reaktivität: Human, Maus WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6258184
  • Target Alle GPR52 Antikörper anzeigen
    GPR52 (G Protein-Coupled Receptor 52 (GPR52))
    Bindungsspezifität
    • 13
    • 9
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reaktivität
    • 33
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 33
    Kaninchen
    Klonalität
    • 33
    Polyklonal
    Konjugat
    • 20
    • 3
    • 3
    • 3
    • 2
    • 2
    Dieser GPR52 Antikörper ist unkonjugiert
    Applikation
    • 23
    • 22
    • 10
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Spezifität
    GPR52 Antibody detects endogenous levels of total GPR52.
    Homologie
    Pig,Bovine,Xenopus
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human GPR52, corresponding to a region within the internal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product GPR52 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Haltbarkeit
    12 months
  • Target
    GPR52 (G Protein-Coupled Receptor 52 (GPR52))
    Andere Bezeichnung
    GPR52 (GPR52 Produkte)
    Synonyme
    GPR52 antikoerper, EG620246 antikoerper, G protein-coupled receptor 52 antikoerper, GPR52 antikoerper, Gpr52 antikoerper
    Hintergrund

    Description: Gs-coupled receptor activated by antipsychotics reserpine leading to an increase in intracellular cAMP and its internalization (PubMed:24587241). May play a role in locomotor activity through modulation of dopamine, NMDA and ADORA2A-induced locomotor activity. These behavioral changes are accompanied by modulation of the dopamine receptor signaling pathway in striatum (PubMed:24587241). Modulates HTT level via cAMP-dependent but PKA independent mechanisms throught activation of RAB39B that translocates HTT to the endoplasmic reticulum, thus avoiding proteasome degradation (PubMed:25738228).

    Gene: GPR52

    Molekulargewicht
    41 kDa,
    Gen-ID
    9293
    UniProt
    Q9Y2T5
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