CDK10 Antikörper (N-Term)

Produktnummer ABIN6258014

Produktdetails anti-CDK10 Antikörper

Target: CDK10 (Cyclin-Dependent Kinase 10 (CDK10))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDK10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: CDK10 Antibody detects endogenous levels of total CDK10.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Dog,Chicken,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CDK10, corresponding to a region within N-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu CDK10

Target: CDK10 (Cyclin-Dependent Kinase 10 (CDK10))

Andere Bezeichnung: CDK10 (CDK10 Produkte)

Synonyme: PISSLRE antikoerper, BC017131 antikoerper, zgc:110252 antikoerper, DDBDRAFT_0216532 antikoerper, DDBDRAFT_0229427 antikoerper, DDB_0216532 antikoerper, DDB_0229427 antikoerper, cdc2rk antikoerper, NV16107 antikoerper, cyclin dependent kinase 10 antikoerper, cyclin-dependent kinase 10 antikoerper, CDK family protein kinase antikoerper, hypothetical protein antikoerper, cyclin-dependent kinase 10 L homeolog antikoerper, CDK10 antikoerper, Cdk10 antikoerper, cdk10 antikoerper, LOC5566134 antikoerper, cdk10.L antikoerper

Hintergrund:

Description: Cyclin-dependent kinase that phosphorylates the transcription factor ETS2 (in vitro) and positively controls its proteasomal degradation (in cells) (PubMed:24218572). Involved in the regulation of actin cytoskeleton organization through the phosphorylation of actin dynamics regulators such as PKN2. Is a negative regulator of ciliogenesis through phosphorylation of PKN2 and promotion of RhoA signaling (PubMed:27104747).

Gene: CDK10

Molekulargewicht: 43 kDa

Gen-ID: 8558

UniProt: Q15131