CC2D1A Antikörper (Internal Region)

Produktnummer ABIN6257986

Produktdetails anti-CC2D1A Antikörper

Target: CC2D1A (Coiled-Coil and C2 Domain Containing 1A (CC2D1A))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CC2D1A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: CC2D1A Antibody detects endogenous levels of total CC2D1A.

Homologie: Pig,Bovine,Horse,Sheep,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CC2D1A, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu CC2D1A

Target: CC2D1A (Coiled-Coil and C2 Domain Containing 1A (CC2D1A))

Andere Bezeichnung: CC2D1A (CC2D1A Produkte)

Synonyme: mrt3 antikoerper, freud-1 antikoerper, FREUD-1 antikoerper, Freud-1/Aki1 antikoerper, MRT3 antikoerper, BC016188 antikoerper, Freud-1 antikoerper, Tape antikoerper, RGD1306108 antikoerper, coiled-coil and C2 domain containing 1A antikoerper, CC2D1A antikoerper, cc2d1a antikoerper, Cc2d1a antikoerper

Hintergrund:

Description: Transcription factor that binds specifically to the DRE (dual repressor element) and represses HTR1A gene transcription in neuronal cells. The combination of calcium and ATP specifically inactivates the binding with FRE. May play a role in the altered regulation of HTR1A associated with anxiety and major depression. Mediates HDAC-independent repression of HTR1A promoter in neuronal cell. Performs essential function in controlling functional maturation of synapses (By similarity). Plays distinct roles depending on its localization. When cytoplasmic, acts as a scaffold protein in the PI3K/PDK1/AKT pathway. Repressor of HTR1A when nuclear. In the centrosome, regulates spindle pole localization of the cohesin subunit SCC1/RAD21, thereby mediating centriole cohesion during mitosis.

Gene: CC2D1A

Molekulargewicht: 130 kDa

Gen-ID: 54862

UniProt: Q6P1N0