CHAF1A Antikörper (Internal Region)

Produktnummer ABIN6257706

Produktdetails anti-CHAF1A Antikörper

Target: CHAF1A (Chromatin Assembly Factor 1, Subunit A (p150) (CHAF1A))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CHAF1A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: CAF1A Antibody detects endogenous levels of total CAF1A.

Homologie: Bovine,Sheep,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CAF1A, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu CHAF1A

Target: CHAF1A (Chromatin Assembly Factor 1, Subunit A (p150) (CHAF1A))

Andere Bezeichnung: CHAF1A (CHAF1A Produkte)

Synonyme: CHAF1A antikoerper, CAF-1 antikoerper, CAF1 antikoerper, CAF1B antikoerper, CAF1P150 antikoerper, P150 antikoerper, AL023013 antikoerper, AL024058 antikoerper, Cac1p antikoerper, CAF-1P150 antikoerper, CAF-I-p150 antikoerper, CAF-Ip150 antikoerper, caip150 antikoerper, wu:fd14g10 antikoerper, zgc:153930 antikoerper, chaf1a-b antikoerper, xp150 antikoerper, chromatin assembly factor 1 subunit A antikoerper, chromatin assembly factor 1, subunit A (p150) antikoerper, chromatin assembly factor 1 subunit A S homeolog antikoerper, Chaf1a antikoerper, CHAF1A antikoerper, LOC100447657 antikoerper, chaf1a antikoerper, chaf1a.S antikoerper

Hintergrund:

Description: Core component of the CAF-1 complex, a complex thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA, histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. CHAF1A binds to histones H3 and H4. It may play a role in heterochromatin maintenance in proliferating cells by bringing newly synthesized cbx proteins to heterochromatic DNA replication foci (By similarity).

Gene: CHAF1A

Molekulargewicht: 150 kDa

Gen-ID: 10036

UniProt: Q13111