ELL2 Antikörper (Internal Region)

Produktnummer ABIN6257461

Produktdetails anti-ELL2 Antikörper

Target: ELL2 (Elongation Factor, RNA Polymerase II, 2 (ELL2))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ELL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: ELL2 Antibody detects endogenous levels of total ELL2.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human ELL2, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu ELL2

Target: ELL2 (Elongation Factor, RNA Polymerase II, 2 (ELL2))

Andere Bezeichnung: ELL2 (ELL2 Produkte)

Synonyme: cb244 antikoerper, fb78f03 antikoerper, sb:cb244 antikoerper, im:3814960 antikoerper, wu:fb78f03 antikoerper, xell2 antikoerper, MGC82755 antikoerper, ELL2 antikoerper, elongation factor for RNA polymerase II 2 antikoerper, elongation factor, RNA polymerase II, 2 antikoerper, elongation factor, RNA polymerase II 2 S homeolog antikoerper, elongation factor, RNA polymerase II 2 antikoerper, elongation factor RNA polymerase II 2 antikoerper, ELL2 antikoerper, ell2 antikoerper, ell2.S antikoerper, Ell2 antikoerper

Hintergrund:

Description: Elongation factor component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III (PubMed:22195968). Plays a role in immunoglobulin secretion in plasma cells: directs efficient alternative mRNA processing, influencing both proximal poly(A) site choice and exon skipping, as well as immunoglobulin heavy chain (IgH) alternative processing. Probably acts by regulating histone modifications accompanying transition from membrane-specific to secretory IgH mRNA expression.

Gene: ELL2

Molekulargewicht: 72 kDa

Gen-ID: 22936

UniProt: O00472