GPR161 Antikörper (Internal Region)
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- Target Alle GPR161 Antikörper anzeigen
- GPR161 (G Protein-Coupled Receptor 161 (GPR161))
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Bindungsspezifität
- Internal Region
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser GPR161 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Spezifität
- GPR161 Antibody detects endogenous levels of total GPR161.
- Homologie
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human GPR161, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product GPR161 Primärantikörper
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anti-G Protein-Coupled Receptor 161 (GPR161) (Cytoplasmic Domain) antibody
GPR161 Reaktivität: Human, Affe, Hamster IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-G Protein-Coupled Receptor 161 (GPR161) (Middle Region) antibodyGPR161 Reaktivität: Human, Maus, Ratte, Meerschweinchen, Rind (Kuh), Hund, Pferd, Kaninchen WB Wirt: Kaninchen Polyclonal unconjugated
anti-G Protein-Coupled Receptor 161 (GPR161) (AA 1-28) antibodyGPR161 Reaktivität: Human WB, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-G Protein-Coupled Receptor 161 (GPR161) antibodyGPR161 Reaktivität: Human, Maus WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-G Protein-Coupled Receptor 161 (GPR161) (C-Term) antibodyGPR161 Reaktivität: Human, Rind (Kuh), Hund, Pferd, Kaninchen, Schwein, Affe IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-G Protein-Coupled Receptor 161 (GPR161) (AA 362-460) antibodyGPR161 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 1B2 unconjugated
anti-G Protein-Coupled Receptor 161 (GPR161) (C-Term) antibodyGPR161 Reaktivität: Human, Maus, Meerschweinchen, Rind (Kuh), Hund, Pferd, Schwein WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-G Protein-Coupled Receptor 161 (GPR161) (N-Term) antibodyGPR161 Reaktivität: Human, Maus, Meerschweinchen, Schwein, Affe WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-G Protein-Coupled Receptor 161 (GPR161) (AA 201-250) antibodyGPR161 Reaktivität: Human, Maus, Rind (Kuh), Schwein, Affe WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-G Protein-Coupled Receptor 161 (GPR161) (N-Term) antibodyGPR161 Reaktivität: Human, Maus, Ratte, Meerschweinchen, Hund, Pferd, Kaninchen, Schwein WB, IHC Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Haltbarkeit
- 12 months
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- Target
- GPR161 (G Protein-Coupled Receptor 161 (GPR161))
- Andere Bezeichnung
- GPR161 (GPR161 Produkte)
- Synonyme
- RE2 antikoerper, Gm208 antikoerper, Gm208Gpr antikoerper, vl antikoerper, RGD1563245 antikoerper, si:bz20i5.4 antikoerper, si:rp71-20i5.4 antikoerper, G protein-coupled receptor 161 antikoerper, GPR161 antikoerper, Gpr161 antikoerper, gpr161 antikoerper
- Hintergrund
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Description: Key negative regulator of Shh signaling, which promotes the processing of GLI3 into GLI3R during neural tube development. Recruited by TULP3 and the IFT-A complex to primary cilia and acts as a regulator of the PKA-dependent basal repression machinery in Shh signaling by increasing cAMP levels, leading to promote the PKA-dependent processing of GLI3 into GLI3R and repress the Shh signaling. In presence of SHH, it is removed from primary cilia and is internalized into recycling endosomes, preventing its activity and allowing activation of the Shh signaling. Its ligand is unknown (By similarity).
Gene: GPR161
- Molekulargewicht
- 65 kDa
- Gen-ID
- 23432
- UniProt
- Q8N6U8
- Pathways
- cAMP Metabolic Process
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