EPHA1 Antikörper (Internal Region)
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- Target Alle EPHA1 Antikörper anzeigen
- EPHA1 (Ephrin Type A Receptor 1 (EPHA1))
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Bindungsspezifität
- Internal Region
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser EPHA1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- EPHA1 Antibody detects endogenous levels of total EPHA1.
- Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human EPHA1, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product EPHA1 Primärantikörper
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- Applikationshinweise
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- EPHA1 (Ephrin Type A Receptor 1 (EPHA1))
- Andere Bezeichnung
- EPHA1 (EPHA1 Produkte)
- Synonyme
- EPH antikoerper, EPHT antikoerper, EPHT1 antikoerper, 5730453L17Rik antikoerper, AL033318 antikoerper, Eph antikoerper, Esk antikoerper, EPHA9 antikoerper, EPH receptor A1 antikoerper, Eph receptor A1 antikoerper, EPHA1 antikoerper, Epha1 antikoerper
- Hintergrund
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Description: Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds with a low affinity EFNA3 and EFNA4 and with a high affinity to EFNA1 which most probably constitutes its cognate/functional ligand. Upon activation by EFNA1 induces cell attachment to the extracellular matrix inhibiting cell spreading and motility through regulation of ILK and downstream RHOA and RAC. Plays also a role in angiogenesis and regulates cell proliferation. May play a role in apoptosis.
Gene: EPHA1
- Molekulargewicht
- 108 kDa
- Gen-ID
- 2041
- UniProt
- P21709
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