CD57 Antikörper

Produktnummer ABIN6252639

Produktdetails anti-CD57 Antikörper

Target: CD57 (B3GAT1) (beta-1,3-Glucuronyltransferase 1 (Glucuronosyltransferase P) (B3GAT1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD57 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: Does not react with rat

Aufreinigung: PEG precipitation

Immunogen: Human peripheral blood mononuclear cells were used as the immunogen for the CD57 antibody.

Klon: HNK-1 or Leu-7

Isotyp: IgM kappa

Anwendungsinformationen

Applikationshinweise: Western blot: 2-4 μg/mL

Flow Cytometry: 0.5-1 μg/million cells in 0.1ml

Immunofluorescence: 0.5-1 μg/mL

Immunohistochemistry (FFPE): 2-4 μg/mL for 30 min at RT (1)

Prediluted format : incubate for 30 min at RT (2)

Optimal dilution of the CD57 antibody should be determined by the researcher.

1. Staining of formalin-fixed tissues requires boiling tissue sections in 10  mM Tris with 1  mM EDTA,  pH 9.0, for 10-20 min followed by cooling at RT for 20 min
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and Store at -20C. Avoid freez-thaw cycles.

Details zu CD57

Target: CD57 (B3GAT1) (beta-1,3-Glucuronyltransferase 1 (Glucuronosyltransferase P) (B3GAT1))

Andere Bezeichnung: CD57 (B3GAT1 Produkte)

Synonyme: CD57 antikoerper, GLCATP antikoerper, GLCUATP antikoerper, HNK1 antikoerper, LEU7 antikoerper, NK-1 antikoerper, NK1 antikoerper, 0710007K08Rik antikoerper, AI846286 antikoerper, GlcAT-P antikoerper, Glcatp antikoerper, Hnk1 antikoerper, Hnk-1 antikoerper, b3gat1 antikoerper, si:dkey-22o20.1 antikoerper, cd57 antikoerper, glcatp antikoerper, glcuatp antikoerper, hnk-1 antikoerper, hnk1 antikoerper, leu7 antikoerper, nk-1 antikoerper, nk1 antikoerper, beta-1,3-glucuronyltransferase 1 antikoerper, beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) antikoerper, beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) a antikoerper, beta-1,3-glucuronyltransferase 1 L homeolog antikoerper, B3GAT1 antikoerper, B3gat1 antikoerper, b3gat1a antikoerper, b3gat1.L antikoerper

Hintergrund: Anti-CD57 marks a subset of lymphocytes known as natural killer (NK) cells. Follicular center cell lymphomas often contain many NK cells within the neoplastic follicles. Anti-CD57 also stains neuroendocrine cells and their derived tumors, including carcinoid tumor and medulloblastoma. Anti-CD57 can also be useful in separating type B3 thymoma from thymic carcinoma when combined with a panel that includes antibodies against GLUT1, CD5, and CEA.

Gen-ID: 27087

UniProt: Q9P2W7

Pathways: Glycosaminoglycan Metabolic Process