SOX2 Antikörper (AA 176-305)

Produktnummer ABIN6252526

Produktdetails anti-SOX2 Antikörper

Target: SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))

Bindungsspezifität: AA 176-305

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SOX2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: Protein G affinity chromatography

Immunogen: Amino acids 176-305 of the human protein were used as the immunogen for the SOX-2 antibody.

Klon: SOX2-1791

Isotyp: IgG2b kappa

Anwendungsinformationen

Applikationshinweise: ELISA: 2-4 μg/mL, order BSA-free formulation for coating

Flow Cytometry: 0.5-1 μg/million cells in 0.1ml

Immunofluorescence: 1-2 μg/mL

Western blot: 0.5-1 μg/mL

Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT

Optimal dilution of the SOX-2 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and Store at -20C. Avoid freez-thaw cycles.

Details zu SOX2

Target: SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))

Andere Bezeichnung: SOX2 (SOX2 Produkte)

Synonyme: ANOP3 antikoerper, MCOPS3 antikoerper, RGD1565646 antikoerper, Sox-2 antikoerper, lcc antikoerper, ysb antikoerper, cb236 antikoerper, wu:fb83g04 antikoerper, wu:fc14d07 antikoerper, zgc:65860 antikoerper, zgc:77389 antikoerper, SRY-box2 antikoerper, Xsox-2 antikoerper, anop3 antikoerper, mcops3 antikoerper, sox-2 antikoerper, SRY-box 2 antikoerper, SRY box 2 antikoerper, SRY (sex determining region Y)-box 2 antikoerper, SRY-box 2 S homeolog antikoerper, SOX2 antikoerper, Sox2 antikoerper, sox2 antikoerper, sox2.S antikoerper

Hintergrund: SOX2 is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. At present, 30 Sox genes have been identified. SOX2 is required for stem cell maintenance in the central nervous system, and it also regulates gene expression in the stomach. SOX2 is necessary for regulating multiple transcription factors that affect Oct 3/4 expression. An essential function of SOX2 is to stabilize embryonic stem cells in a pluripotent state by maintaining the requisite level of Oct 3/4 expression.

Gen-ID: 6657

UniProt: P48431

Pathways: Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis