S1PR1 Antikörper (C-Term)

Produktnummer ABIN6252492

Produktdetails anti-S1PR1 Antikörper

Target: S1PR1 (Sphingosine-1-Phosphate Receptor 1 (S1PR1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser S1PR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Protein A affinity chromatography

Immunogen: A recombinant protein fragment from the C-terminal portion of human EDG1 was used as the immunogen for this antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot: 4-6 μg/mL

Provided assay concentrations are suggestions only, EDG1 antibody titration may be required for optimal results.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and Store at -20C. Avoid freez-thaw cycles.

Details zu S1PR1

Target: S1PR1 (Sphingosine-1-Phosphate Receptor 1 (S1PR1))

Andere Bezeichnung: EDG1 (S1PR1 Produkte)

Synonyme: CD363 antikoerper, CHEDG1 antikoerper, D1S3362 antikoerper, ECGF1 antikoerper, EDG-1 antikoerper, EDG1 antikoerper, S1P1 antikoerper, AI849002 antikoerper, Edg1 antikoerper, Lpb1 antikoerper, S1p antikoerper, S1p1 antikoerper, S1P receptor 1 antikoerper, S1P receptor Edg-1 antikoerper, edg1 antikoerper, etID43307.22 antikoerper, s1p1 antikoerper, wu:fb98f05 antikoerper, s1pr1 antikoerper, xts1p1 antikoerper, sphingosine-1-phosphate receptor 1 antikoerper, sphingosine-1-phosphate receptor 1 L homeolog antikoerper, S1PR1 antikoerper, S1pr1 antikoerper, s1pr1 antikoerper, s1pr1.L antikoerper

Hintergrund: EDG1 (Endothelial differentiation gene 1), also called Sphingosine-1-phosphate receptor 1 (S1PR1) is the G-protein coupled receptor for Sphingosine 1-phosphate (S1P). Via its interaction with S1P, EDG1 is involved in a number of cellular processes. The binding of S1P leads to angiogenesis and tumor cell motility in cancer, and this interaction also participates in the formation of cell-cell adherens junctions. During embryogenesis, it regulates vascularization. EDG1 interacts with the serotonin receptor 5-HT1AR in the central nervous system. It is also a regulator of innate and adaptive immunity by signaling the release of T-cells from lymph nodes.

Gen-ID: 1901

UniProt: P21453

Pathways: Signaling Events mediated by VEGFR1 and VEGFR2