Moesin Antikörper

Produktnummer ABIN6252085

Produktdetails anti-Moesin Antikörper

Target: Moesin (MSN)

Reaktivität: Human, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Moesin Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Aufreinigung: Protein G affinity chromatography

Immunogen: Recombinant human protein was used as the immunogen for this Moesin antibody.

Klon: SPM562

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Flow Cytometry: 0.5-1 μg/million cells in 0.1ml

Immunofluorescence: 0.5-1 μg/mL

Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)

Prediluted format : incubate for 30 min at RT (2)

The optimal dilution of the Moesin antibody for each application should be determined by the researcher.

1. Staining of formalin-fixed tissues requires boiling tissue sections in 10  mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and Store at -20C. Avoid freez-thaw cycles.

Details zu Moesin

Target: Moesin (MSN)

Andere Bezeichnung: Moesin (MSN Produkte)

Synonyme: CG10701 antikoerper, D17 antikoerper, Dmel\\CG10701 antikoerper, Dmoe antikoerper, EMR1 antikoerper, ERM antikoerper, Emr1 antikoerper, anon-WO03040301.155 antikoerper, anon-WO03040301.157 antikoerper, anon-WO03040301.159 antikoerper, anon-WO03040301.161 antikoerper, dMoe antikoerper, gma antikoerper, l(1)G0067 antikoerper, l(1)G0323 antikoerper, l(1)G0404 antikoerper, l(1)G0415 antikoerper, moe antikoerper, moesin/ezrin/radixin homolog mRNA antikoerper, cb567 antikoerper, rdx antikoerper, wu:fb14b03 antikoerper, zgc:85640 antikoerper, MSN antikoerper, C78546 antikoerper, moesin antikoerper, Moesin antikoerper, moesin a antikoerper, moesin L homeolog antikoerper, MSN antikoerper, Moe antikoerper, msna antikoerper, msn.L antikoerper, moes antikoerper, Msn antikoerper

Hintergrund: Recognizes 78  kDa moesin protein. Moesin, a member of the Talin-4.1 superfamily, is a linking protein of the submembraneous actin cytoskeleton. It is expressed in variable amounts in cells of different phenotypes such as macrophages, lymphocytes, fibroblastic, endothelial, epithelial, and neuronal cell lines but not in blood cells. The ERM proteins, ezrin, radixin, and moesin are involved in a variety of cellular functions, such as cell adhesion, migration, and the organization of cell surface structures, and are highly homologous, both in protein sequence and in functional activity, with merlin/schwannomin, a neurofibromatosis-2-associated tumor-suppressor protein. Cell lines of epithelial and mesothelial origin contain both moesin and radixin whereas cells of endothelial and lymphoid origin express moesin.

Gen-ID: 4478

UniProt: P26038

Pathways: Asymmetric Protein Localization