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CD7 Antikörper

CD7 Reaktivität: Human FACS, IF Wirt: Maus Monoclonal HuLy-m2 unconjugated

Produktnummer ABIN6251913

Datenblatt (PDF)

Target Alle CD7 Antikörper anzeigen

CD7
Reaktivität
186

25

10

10

7
Human
Wirt
101

85

1

1
Maus
Passende Sekundärantikörper
Klonalität
104

83

1
Monoklonal
Konjugat
66

19

15

14

10

8

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser CD7 Antikörper ist unkonjugiert
Applikation
109

67

52

30

25

16

12

12

7

5

3

2

1

1

1

1

1

1

1

1
Flow Cytometry (FACS), Immunofluorescence (IF)

Aufreinigung

Protein G affinity chromatography

Immunogen

Human thymocytes were used as the immunogen for the CD7 antibody.

Klon

HuLy-m2

Isotyp

IgG2a kappa

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Applikationshinweise

Flow Cytometry: 0.5-1 μg/million cells in 0.1ml

Immunofluorescence: 0.5-1 μg/mL

Optimal dilution of the CD7 antibody should be determined by the researcher.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

0.2 mg/mL

Buffer

PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

-20 °C

Informationen zur Lagerung

Aliquot and Store at -20C. Avoid freez-thaw cycles.
Target

CD7

Andere Bezeichnung

CD7 (CD7 Produkte)

Synonyme

GP40 antikoerper, LEU-9 antikoerper, TP41 antikoerper, Tp40 antikoerper, CD7 molecule antikoerper, CD7 antigen antikoerper, Cd7 molecule antikoerper, CD7 antikoerper, Cd7 antikoerper

Hintergrund

Recognizes a protein of 40  kDa, identified as CD7 (Workshop IV, Code T165). CD7 is a member of the immunoglobulin gene superfamily. Its N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxyl-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. It is also found on natural killer cells, a small subpopulation of normal B cells and on malignant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3'-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation.

Gen-ID

924

UniProt

P09564

Pathways

Cell-Cell Junction Organization