This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This RAB3GAP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 943-972 amino acids from the C-terminal region of human RAB3GAP2.
RAB3GAP2
Reaktivität: Human
ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro)
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
WB: 1:1000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Haltbarkeit
6 months
Carpanini, McKie, Thomson, Wright, Gordon, Roche, Handley, Morrison, Brownstein, Wishart, Cousin, Gillingwater, Aligianis, Jackson: "A novel mouse model of Warburg Micro syndrome reveals roles for RAB18 in eye development and organisation of the neuronal cytoskeleton." in: Disease models & mechanisms, Vol. 7, Issue 6, pp. 711-22, (2015) (PubMed).
Target
RAB3GAP2
(RAB3 GTPase Activating Protein Subunit 2 (Non-Catalytic) (RAB3GAP2))
RAB3GAP2 belongs to the RAB3 protein family, members of which are involved in regulated exocytosis of neurotransmitters and hormones. This protein forms the Rab3 GTPase-activating complex with RAB3GAP1, where it constitutes the regulatory subunit, whereas the latter functions as the catalytic subunit. This gene has the highest level of expression in the brain, consistent with it having a key role in neurodevelopment.