This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This CLEC16A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 773-805 amino acids from the C-terminal region of human CLEC16A.
CLEC16A antikoerper, Gop-1 antikoerper, KIAA0350 antikoerper, 4932416N17Rik antikoerper, curt antikoerper, mKIAA0350 antikoerper, RGD1305773 antikoerper, C-type lectin domain family 16 member A antikoerper, C-type lectin domain containing 16A antikoerper, C-type lectin domain family 16, member A antikoerper, CLEC16A antikoerper, clec16a antikoerper, Clec16a antikoerper
Hintergrund
Regulator of mitophagy through the upstream regulation of the RNF41/NRDP1-PARK2 pathway. Mitophagy is a selective form of autophagy necessary for mitochondrial quality control. The RNF41/NRDP1-PARK2 pathway regulates autophagosome-lysosome fusion during late mitophagy. May protect RNF41/NRDP1 from proteosomal degradation, RNF41/NRDP1 which regulates proteosomal degradation of PARK2. Plays a key role in beta cells functions by regulating mitophagy/autophagy and mitochondrial health.