C1orf38 Antikörper (C-Term)

Produktnummer ABIN6242717

Produktdetails anti-C1orf38 Antikörper

Target: C1orf38 (Chromosome 1 Open Reading Frame 38 (C1orf38))

Bindungsspezifität: AA 613-641, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C1orf38 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ICB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 613-641 amino acids from the C-terminal region of human ICB1.

Klon: RB24946

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-C1orf38 Antikörper (ABIN6242717)

Hartweger, Schweighoffer, Davidson, Peirce, Wack, Tybulewicz: "Themis2 is not required for B cell development, activation, and antibody responses." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 193, Issue 2, pp. 700-7, (2014) (PubMed).

Peirce, Brook, Morrice, Snelgrove, Begum, Lanfrancotti, Notley, Hussell, Cope, Wait: "Themis2/ICB1 is a signaling scaffold that selectively regulates macrophage Toll-like receptor signaling and cytokine production." in: PLoS ONE, Vol. 5, Issue 7, pp. e11465, (2010) (PubMed).

Details zu C1orf38

Target: C1orf38 (Chromosome 1 Open Reading Frame 38 (C1orf38))

Andere Bezeichnung: ICB1 (C1orf38 Produkte)

Synonyme: C1orf38 antikoerper, ICB-1 antikoerper, thymocyte selection associated family member 2 antikoerper, THEMIS2 antikoerper, Themis2 antikoerper

Hintergrund: Involved in cell adhesion. There are 4 isoforms produced by alternative splicing.

Molekulargewicht: 72049

NCBI Accession: NP_001034566, NP_001099026, NP_004839

UniProt: Q5TEJ8