eIF4EBP1 Antikörper (pSer111)
(1 reference)Kurzübersicht für eIF4EBP1 Antikörper (pSer111) (ABIN6241036)
Target
Alle eIF4EBP1 (EIF4EBP1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- pSer111
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Homologie
- M, Rat
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Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This EIF4EBP1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S111 of human EIF4EBP1.
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Isotyp
- Ig Fraction
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anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) (C-Term) antibody
EIF4EBP1 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) (pThr37), (pThr46) antibodyEIF4EBP1 Reaktivität: Human, Maus WB, ELISA, IHC (p), IF (cc), IF (p), FACS, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) (pSer65) antibodyEIF4EBP1 Reaktivität: Human IHC, ELISA, ICC, FACS Wirt: Maus Monoclonal 1E2E7 unconjugated
anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) (pSer65) antibodyEIF4EBP1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) (AA 1-118) antibodyEIF4EBP1 Reaktivität: Human WB, ELISA, IF, PLA Wirt: Maus Monoclonal 4F3-H2 unconjugated
anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) (pThr36) antibodyEIF4EBP1 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) (AA 2-111) antibodyEIF4EBP1 Reaktivität: Human IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) (AA 2-118) antibodyEIF4EBP1 Reaktivität: Human WB, IHC, ICC, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) (AA 31-61) antibodyEIF4EBP1 Reaktivität: Human WB, IHC (p), FACS Wirt: Kaninchen Polyclonal RB11691 unconjugated
anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) (AA 101-118) antibodyEIF4EBP1 Reaktivität: Human, Maus, Ratte, Kaninchen, Hamster WB, IHC, IHC (p), GS Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- DB: 1:500
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Haltbarkeit
- 6 months
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: "Association of maternal mRNA and phosphorylated EIF4EBP1 variants with the spindle in mouse oocytes: localized translational control supporting female meiosis in mammals." in: Genetics, Vol. 195, Issue 2, pp. 349-58, (2014) (PubMed).
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: "Association of maternal mRNA and phosphorylated EIF4EBP1 variants with the spindle in mouse oocytes: localized translational control supporting female meiosis in mammals." in: Genetics, Vol. 195, Issue 2, pp. 349-58, (2014) (PubMed).
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- eIF4EBP1 (EIF4EBP1) (Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))
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Andere Bezeichnung
- EIF4EBP1
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Hintergrund
- EIF4EBP1 is a member of a family of translation repressor proteins. This protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of EIF4EBP1 with eIF4E inhibits complex assembly and represses translation. EIF4EBP1 is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
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Molekulargewicht
- 12580
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NCBI Accession
- NP_004086
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UniProt
- Q13541
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Pathways
- MAPK Signalweg, PI3K-Akt Signalweg, RTK Signalweg, AMPK Signaling, Regulation of Cell Size, BCR Signaling
Target
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