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eIF4EBP1 Antikörper (pSer111)

Name: eIF4EBP1 Antikörper (pSer111)
SKU: ABIN6241036
Price: 434.77 EUR
Availability: InStock

Dieses Anti-eIF4EBP1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von eIF4EBP1 in DB. Geeignet für Human. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Dot blot analysis of anti-EIF4EBP1-p Phospho-specific Pab (R) on nitrocellulose membrane. (eIF4EBP1 Antikörper (pSer111))

1 image

(1 reference)

Produktnummer ABIN6241036

Datenblatt (PDF)

Kurzübersicht für eIF4EBP1 Antikörper (pSer111) (ABIN6241036)

Target

Alle eIF4EBP1 (EIF4EBP1) Antikörper anzeigen

eIF4EBP1 (EIF4EBP1) (Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))

Reaktivität

Human

Wirt

Kaninchen

Klonalität

Polyklonal

Konjugat

Dieser eIF4EBP1 Antikörper ist unkonjugiert

Applikation

Dot Blot (DB)

Klon

RB13351

Discover our top product EIF4EBP1 Primärantikörper

Bindungsspezifität
28

20

20

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16

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11

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pSer111

Homologie

M, Rat

Aufreinigung

This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen

This EIF4EBP1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S111 of human EIF4EBP1.

Isotyp

Ig Fraction
anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) (pThr37), (pThr46) antibody
EIF4EBP1 Reaktivität: Human, Maus WB, ELISA, IHC (p), IF (cc), IF (p), FACS, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) (C-Term) antibody
EIF4EBP1 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) (pSer65) antibody
EIF4EBP1 Reaktivität: Human IHC, ELISA, ICC, FACS Wirt: Maus Monoclonal 1E2E7 unconjugated

anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) (pSer65) antibody
EIF4EBP1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) (AA 1-118) antibody
EIF4EBP1 Reaktivität: Human WB, ELISA, IF, PLA Wirt: Maus Monoclonal 4F3-H2 unconjugated

anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) (pThr36) antibody
EIF4EBP1 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) (AA 2-111) antibody
EIF4EBP1 Reaktivität: Human IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) (AA 2-118) antibody
EIF4EBP1 Reaktivität: Human WB, IHC, ICC, IP Wirt: Kaninchen Polyclonal unconjugated

anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) (AA 31-61) antibody
EIF4EBP1 Reaktivität: Human WB, IHC (p), FACS Wirt: Kaninchen Polyclonal RB11691 unconjugated

anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) (AA 101-118) antibody
EIF4EBP1 Reaktivität: Human, Maus, Ratte, Kaninchen, Hamster WB, IHC, IHC (p), GS Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

DB: 1:500

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Haltbarkeit

6 months
Romasko, Amarnath, Midic, Latham: "Association of maternal mRNA and phosphorylated EIF4EBP1 variants with the spindle in mouse oocytes: localized translational control supporting female meiosis in mammals." in: Genetics, Vol. 195, Issue 2, pp. 349-58, (2014) (PubMed).
Target

eIF4EBP1 (EIF4EBP1) (Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))

Andere Bezeichnung

EIF4EBP1

Hintergrund

EIF4EBP1 is a member of a family of translation repressor proteins. This protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of EIF4EBP1 with eIF4E inhibits complex assembly and represses translation. EIF4EBP1 is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.

Molekulargewicht

12580

NCBI Accession

NP_004086

UniProt

Q13541

Pathways

MAPK Signalweg, PI3K-Akt Signalweg, RTK Signalweg, AMPK Signaling, Regulation of Cell Size, BCR Signaling