FTL Antikörper (AA 38-165) (CF®594)

Produktnummer ABIN6191651

Produktdetails anti-FTL Antikörper (CF®594)

Target: FTL (Ferritin, Light Polypeptide (FTL))

Bindungsspezifität: AA 38-165

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser FTL Antikörper ist konjugiert mit CF®594

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Verwendungszweck: Mouse Monoclonal anti-Ferritin, Light chain (FTL/1388), CF594 Conjugate

Produktmerkmale: Mammalian ferritins consist of 24 subunits made up of 2 types of polypeptide chains, ferritin heavy chain and ferritin light chain. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe (II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe (III). Light chain ferritin is involved in cataracts by at least two mechanisms, hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of ageing-related cataracts. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant human FTL protein fragment (aa 38-165) (exact sequence is proprietary)

Klon: FTL-1388

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Immunohistology (formalin) 0.1-0.2 μg/mL

• Flow cytometry 0.1-0.2 μg/million cells Immunofluorescence 0.1-0.2 μg/mL
• Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 min
• Optimal dilution for a specific application should be determined by user

Kommentare:

HepG2, HeLa, HL-60 or 293T cells. Pancreas, Liver, Cerebellum or Testis.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from light

Details zu FTL

Target: FTL (Ferritin, Light Polypeptide (FTL))

Andere Bezeichnung: Ferritin, Light chain (FTL Produkte)

Synonyme: NBIA3 antikoerper, apoferritin antikoerper, ferritin antikoerper, fhc antikoerper, fth antikoerper, fth1 antikoerper, fthl6 antikoerper, ftn-2 antikoerper, pig15 antikoerper, plif antikoerper, FT antikoerper, Ftl antikoerper, Ftl-1 antikoerper, L-ferritin antikoerper, FTL antikoerper, Ftl1 antikoerper, FTL2 antikoerper, FTD antikoerper, ferritin light chain antikoerper, ferritin, heavy polypeptide 1 L homeolog antikoerper, ferritin light polypeptide 1 antikoerper, ferritin, light polypeptide antikoerper, ferritin light-chain antikoerper, ferritin light chain 1 antikoerper, FTL antikoerper, fth1.L antikoerper, Ftl1 antikoerper, CpipJ_CPIJ004069 antikoerper, Ftl antikoerper

Hintergrund: Ferritin L chain, Ferritin L subunit, Ferritin light chain, Ferritin light polypeptide, FTL, LFTD, NBIA3

Molekulargewicht: 19-25 kDa

Gen-ID: 2512, 433670

UniProt: P02792

Pathways: Transition Metal Ion Homeostasis