PLGF Antikörper (CF®594)

Produktnummer ABIN6189256

Produktdetails anti-PLGF Antikörper (CF®594)

Target: PLGF (PGF) (Placenta Growth Factor (PGF))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PLGF Antikörper ist konjugiert mit CF®594

Applikation: ELISA, Coating (Coat)

Verwendungszweck: Mouse Monoclonal anti-PLGF (PLGF/94), CF594 Conjugate

Produktmerkmale: The onset of angiogenesis is believed to be an early event in tumorigenesis and may facilitate tumor progression and metastasis. Several growth factors with angiogenic activity have been described. These include Fibroblast Growth Factor (FGF), Platelet Derived Growth Factor (PDGF), Vascular Endothelial Growth Factor (VEGF) and Placenta Growth Factor (PLGF). Placenta growth factor (PLGF) is a secreted protein primarily produced by placental trophoblasts but also expressed in other endothelial cells and tumors. There are three isoforms, PLGF-1, PLGF-2, and PLGF-3. PLGF-2 is expressed up until week 8 in the placenta, the placental tissues continuously express PLGF-1 and PLGF-3 but only PLGF-1 is found in colon and mammary carcinomas. PLGF acts to stimulate angiogenesis, endothelial growth and migration. PLGF is a powerful promoter of tumor growth and is upregulated in some cancers, and PLGF is thought to aid in atherosclerotic lesions and neovascular growth surrounding the lesion. Also, PLGF appears to aid aldosterone mediated atherosclerosis. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant human PLGF protein

Klon: PLGF94

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: ELISA For coating, order Ab without BSA

Kommentare:

HepG2 or HEK293T cells. Human placental and brain tumors.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from light

Details zu PLGF

Target: PLGF (PGF) (Placenta Growth Factor (PGF))

Andere Bezeichnung: PLGF (PGF Produkte)

Synonyme: D12S1900 antikoerper, PGFL antikoerper, PLGF antikoerper, PlGF-2 antikoerper, SHGC-10760 antikoerper, AI854365 antikoerper, PIGF antikoerper, Plgf antikoerper, PlGF antikoerper, placental growth factor antikoerper, placenta growth factor antikoerper, PGF antikoerper, Pgf antikoerper, PLGF antikoerper

Hintergrund: PGFL, PIGF, placental growth factor (PGF), Vascular endothelial growth factor related protein

Molekulargewicht: 18 kDa

Gen-ID: 5228, 252820

UniProt: P49763

Pathways: VEGFR1 Specific Signals