CD19 Antikörper (CF®488A)
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- Target Alle CD19 Antikörper anzeigen
- CD19 (CD19 Molecule (CD19))
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Reaktivität
- Human, Affe, Schimpanse
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD19 Antikörper ist konjugiert mit CF®488A
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Applikation
- Flow Cytometry (FACS), Immunofluorescence (IF)
- Verwendungszweck
- Mouse Monoclonal anti-CD19 (CVID3/429), CF488A Conjugate
- Produktmerkmale
- CD19 is a transmembrane glycoprotein that contains two extracellular immunoglobulin-like domains. CD19 is present in both benign and malignant B-cells and is considered to be the most reliable surface marker of this lineage over a wide range of maturational stages. In normal lymphoid tissue, CD19 is observed in germinal centers, in mantle zone cells, and in scattered cells of the inter-follicular areas. Anti-CD19 exhibits an overall immunoreactivity pattern similar to those of the antibodies against CD20 and CD22. However, in contrast to CD20, expression of CD19 is continuous throughout B-cell development and through terminal differentiation of B-cells into plasma cells. Anti-CD19 positivity is seen in the vast majority of B-cell neoplasms commonly at a lower intensity than normal B-cell counterparts. Plasma cell neoplasms are nearly always negative, as are T-cell neoplasms. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Immunogen
- Recombinant human CD19 protein
- Klon
- CVID3-429
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product CD19 Primärantikörper
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- Applikationshinweise
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Immunofluorescence 0.5-1 μg/mL
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Optimal dilution for a specific application should be determined by user
- Kommentare
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Tonsil, lymph node, or spleen
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 100 μg/mL
- Buffer
- PBS/0.1 % BSA/0.05 % azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Protect from light
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- Target
- CD19 (CD19 Molecule (CD19))
- Andere Bezeichnung
- CD19 (CD19 Produkte)
- Synonyme
- B4 antikoerper, CVID3 antikoerper, AW495831 antikoerper, CD19 antikoerper, CD19 molecule antikoerper, CD19 antigen antikoerper, CD19 antikoerper, Cd19 antikoerper
- Hintergrund
- B-lymphocyte antigen CD19, B-lymphocyte surface antigen B4, CVID3, Leu-12, Lymphocyte Surface Antigen, T-cell surface antigen Leu-12
- Molekulargewicht
- 95 kDa
- Gen-ID
- 930, 652262
- UniProt
- P15391
- Pathways
- Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung
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