SEMA4D/CD100 Antikörper

Produktnummer ABIN6182238

Produktdetails anti-SEMA4D/CD100 Antikörper

Target: SEMA4D/CD100 (SEMA4D) (Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 4D (SEMA4D))

Reaktivität: Human, Pavian

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SEMA4D/CD100 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF)

Verwendungszweck: Mouse Monoclonal anti-CD100 (133-1C6), Purified, with BSA

Produktmerkmale: This antibody recognizes a homodimeric protein comprised of 50 kDa subunits, identified as CD100 (Workshop VI, Code N-L026). It is expressed on majority of haemopoietic cells (B, T, NK and myeloid cells) and is absent from bone marrow, erythrocytes, eosinophils and endothelial cells. Its expression is increased after PHA-activation. CD100 was shown to associate with different partner molecules in T cells such as CD45, a key molecule with protein tyrosine phosphatase activity involved in T-cell transduction, and a Serine kinase. It plays a role in homotypic cell adhesion and in T cell activation. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Aufreinigung: Purified

Immunogen: PHA stimulated human peripheral blood lymphocytes.

Klon: 133-1C6

Isotyp: IgM kappa

Anwendungsinformationen

Applikationshinweise: Does not react with horse, others not tested

• Immunofluorescence 0.5-1 μg/mL
• Flow Cytometry 0.5-1 μg/million cells/0.1 mL
• Optimal dilution for a specific application should be determined by user

Kommentare:

Daudi, Raji, HUT-78, Kg1a, U937, and human lymphocytes. Human tonsils and lymph nodes.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 200 μg/mL

Buffer: PBS/0.05 % BSA/0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Details zu SEMA4D/CD100

Target: SEMA4D/CD100 (SEMA4D) (Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 4D (SEMA4D))

Andere Bezeichnung: CD100 (SEMA4D Produkte)

Synonyme: C9orf164 antikoerper, CD100 antikoerper, M-sema-G antikoerper, SEMAJ antikoerper, coll-4 antikoerper, Semacl2 antikoerper, Semaj antikoerper, Semcl2 antikoerper, COLL-4 antikoerper, semaphorin 4D antikoerper, sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D antikoerper, Sema4d antikoerper, SEMA4D antikoerper

Hintergrund: COLL4, Collapsin4, GR3, M sema G, MSEMA, SEMA4D, Semacl2, SemaH, SEMAJ, Semaphorin C like 2, Semaphorin H, Semaphorin J, Semaphorin-4D, Semcl2

Molekulargewicht: 50 kDa (Monomer)

Gen-ID: 10507, 494406

UniProt: Q92854

Pathways: Regulation of Cell Size