CD1b Antikörper

Produktnummer ABIN6176159

Produktdetails anti-CD1b Antikörper

Target: CD1b (CD1B)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD1b Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF)

Verwendungszweck: Mouse Monoclonal anti-CD1b (RIV12), Purified, BSA-free

Produktmerkmale: The mouse monoclonal antibody recognizes CD1b, a 44 kDa type I glycoprotein associated with beta2-microglobulin. It is expressed on dendritic cells, Langerhans cells, thymocytes, and T acute lymphoblastic leukemia cells. The CD1 multigene family encodes five forms of the CD1 T-cell surface glycoprotein in human, designated CD1A, 1B, 1C, 1D and 1E. CD1, a type 1 membrane protein, has structural similarity to the MHC class I antigen and has been shown to present lipid antigens for recognition by T lymphocytes. Constitutive endocytosis of CD1B molecules and the differential sorting of MHC class II from lysosomes separate peptide- and lipid antigen-presenting molecules during dendritic cell maturation. CD1B is also expressed in interdigitating cells. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Aufreinigung: Purified

Immunogen: Human peripheral lymphocytes

Klon: RIV12

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Immunofluorescence 0.5-1 μg/mLFlow Cytometry 0.5-1 μg/million cells/0.1 mL

Kommentare:

MOLT4 cells. Human thymus.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS (no BSA, no azide)

Konservierungsmittel: Azide free

Details zu CD1b

Target: CD1b (CD1B)

Andere Bezeichnung: CD1b (CD1B Produkte)

Synonyme: CD1 antikoerper, CD1A antikoerper, R1 antikoerper, CD1B3 antikoerper, CD1B antikoerper, CD1-b antikoerper, CD1b molecule antikoerper, T-cell surface glycoprotein CD1b-3 antikoerper, CD1b1 molecule antikoerper, T-cell surface glycoprotein CD1b1 antikoerper, CD1B antikoerper, LOC443423 antikoerper, CD1B1 antikoerper, LOC100720602 antikoerper

Hintergrund: A1 domain, CD1B, Cortical thymocyte antigen CD1B, hTa1 thymocyte antigen, Ly38, T cell surface glycoprotein CD1b, T6/Leu6

Molekulargewicht: 49 kDa

Gen-ID: 910, 1310

UniProt: P29016