Desmin Antikörper (CF®640R)
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- Target Alle Desmin (DES) Antikörper anzeigen
- Desmin (DES)
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Reaktivität
- Human, Maus, Ratte, Huhn, Hamster
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Desmin Antikörper ist konjugiert mit CF®640R
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
- Verwendungszweck
- Mouse Monoclonal anti-Desmin (DES/1711), CF640R Conjugate
- Produktmerkmale
- Cytoskeletal intermediate filaments (IFs) constitute a diverse group of proteins that are expressed in a highly tissue-specific manner. IFs are constructed from two-chain ?-helical coiled-coil molecules arranged on an imperfect helical lattice, and have been widely used as markers for distinguishing individual cell types within a tissue and identifying the origins of metastatic tumors. Vimentin is an IF general marker of cells originating in the mesenchyme. Vimentin and Desmin, a related class III IF, are both expressed during skeletal muscle development. Desmin, a 469 amino acid protein found near the Z line in sarcomeres, is expressed more frequently in adult differentiated state tissues. Anti-desmin detects cells of normal smooth, skeletal, and cardiac muscles. The antibody reacts with leiomyomas, leiomyosarcoma, rhabdomyomas, rhabdomyosarcoma, and perivascular cells of glomus tumors of the skin. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Immunogen
- Recombinant human full-length desmin protein
- Klon
- DES-1711
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product DES Primärantikörper
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- Applikationshinweise
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Immunohistology (formalin) 1-2 μg/mL
- Immunofluorescence 1-2 μg/mL Flow cytometry 0.5-1 μg/million cells
- Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min
- Western blotting 0.5-1 μg/mL
- Optimal dilution for a specific application should be determined by user
- Kommentare
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SJRH30 Cells. Uterus or Leiomyosarcoma
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 100 μg/mL
- Buffer
- PBS/0.1 % BSA/0.05 % azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Protect from light
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- Target
- Desmin (DES)
- Andere Bezeichnung
- Desmin (DES Produkte)
- Synonyme
- DES antikoerper, des-b antikoerper, MGC80853 antikoerper, des antikoerper, csm1 antikoerper, csm2 antikoerper, desm antikoerper, cmd1i antikoerper, MGC75911 antikoerper, LOC100220724 antikoerper, desmin antikoerper, cb290 antikoerper, fb59a12 antikoerper, wu:fb59a12 antikoerper, zgc:109859 antikoerper, CSM1 antikoerper, CSM2 antikoerper, LGMD2R antikoerper, wu:fc11d08 antikoerper, zgc:154009 antikoerper, des-a antikoerper, MGC52614 antikoerper, desmin antikoerper, desmin, gene 1 L homeolog antikoerper, desmin, gene 1 antikoerper, desmin a antikoerper, desmin b antikoerper, desmin, gene 1 S homeolog antikoerper, desmin, gene 2 S homeolog antikoerper, DES antikoerper, des.1.L antikoerper, des.1 antikoerper, des antikoerper, desma antikoerper, Des antikoerper, desmb antikoerper, des.1.S antikoerper, des.2.S antikoerper
- Hintergrund
- CMD1I, CSM1, CSM2, DES, Intermediate filament protein
- Molekulargewicht
- 52 kDa
- Gen-ID
- 1674, 594952
- UniProt
- P17661
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