Moesin Antikörper (CF®594)

Produktnummer ABIN6165751

Produktdetails anti-Moesin Antikörper (CF®594)

Target: Moesin (MSN)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Moesin Antikörper ist konjugiert mit CF®594

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Verwendungszweck: Mouse Monoclonal anti-Moesin (MSN493), CF594 Conjugate

Produktmerkmale: This antibody recognizes 78 kDa moesin protein. Moesin, a member of the talin-4.1 superfamily, is a linking protein of the sub-membranous actin cytoskeleton. It is expressed in variable amounts in cells of different phenotypes such as macrophages, lymphocytes, fibroblastic, endothelial, epithelial, and neuronal cell lines but not in blood cells. The ERM proteins, ezrin, radixin, and moesin are involved in a variety of cellular functions, such as cell adhesion, migration, and the organization of cell surface structures, and are highly homologous, both in protein sequence and in functional activity, with merlin/schwannomin, a neurofibromatosis-2-associated tumor-suppressor protein. Cell lines of epithelial and mesothelial origin contain both moesin and radixin whereas cells of endothelial and lymphoid origin express moesin. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant full-length human Moesin protein

Klon: MSN493

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Does not react with rat, others not known

• Immunohistology (formalin)
• Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes
• Immunofluorescence 0.5-1 μg/mL
• Flow Cytometry 0.5-1 μg/million cells/0.1 mL
• Western blotting 0.5-1 μg/mL
• Optimal dilution for a specific application should be determined by user

Kommentare:

HT-29, CH3LC, or HUVEC cells. Uterus, placenta, tonsil (both B and T lymphocytes), skeletal muscle, thyroid, or kidney.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from light

Details zu Moesin

Target: Moesin (MSN)

Andere Bezeichnung: Moesin (MSN Produkte)

Synonyme: CG10701 antikoerper, D17 antikoerper, Dmel\\CG10701 antikoerper, Dmoe antikoerper, EMR1 antikoerper, ERM antikoerper, Emr1 antikoerper, anon-WO03040301.155 antikoerper, anon-WO03040301.157 antikoerper, anon-WO03040301.159 antikoerper, anon-WO03040301.161 antikoerper, dMoe antikoerper, gma antikoerper, l(1)G0067 antikoerper, l(1)G0323 antikoerper, l(1)G0404 antikoerper, l(1)G0415 antikoerper, moe antikoerper, moesin/ezrin/radixin homolog mRNA antikoerper, cb567 antikoerper, rdx antikoerper, wu:fb14b03 antikoerper, zgc:85640 antikoerper, MSN antikoerper, C78546 antikoerper, moesin antikoerper, Moesin antikoerper, moesin a antikoerper, moesin L homeolog antikoerper, MSN antikoerper, Moe antikoerper, msna antikoerper, msn.L antikoerper, moes antikoerper, Msn antikoerper

Hintergrund: Membrane-organizing extension spike protein, Moesin/anaplastic lymphoma kinase fusion protein, MSN/ALK fusion

Molekulargewicht: 78 kDa

Gen-ID: 4478, 87752

UniProt: P26038

Pathways: Asymmetric Protein Localization