CD7 Antikörper
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- Target Alle CD7 Antikörper anzeigen
- CD7
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD7 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Immunofluorescence (IF)
- Verwendungszweck
- Mouse Monoclonal anti-CD7 (124.1D1), Purified, with BSA
- Produktmerkmale
- This antibody recognizes a protein of 40 kDa, identified as CD7 (Workshop IV, Code T155). CD7 is a member of the immunoglobulin gene superfamily. Its N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxyl-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. It is also found on natural killer cells, a small subpopulation of normal B cells and on malignant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3'-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Aufreinigung
- Purified
- Immunogen
- Human leukocytes
- Klon
- 124-1D1
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product CD7 Primärantikörper
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- Applikationshinweise
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Immunofluorescence 0.5-1 μg/mL
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Optimal dilution for a specific application should be determined by user
- Kommentare
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Jurkat, HUT-78, Molt-4, CEM cells, or human peripheral blood lymphocytes. Lymph node and tonsil.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 200 μg/mL
- Buffer
- PBS/0.05 % BSA/0.05 % azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- Target
- CD7
- Andere Bezeichnung
- CD7 (CD7 Produkte)
- Synonyme
- GP40 antikoerper, LEU-9 antikoerper, TP41 antikoerper, Tp40 antikoerper, CD7 molecule antikoerper, CD7 antigen antikoerper, Cd7 molecule antikoerper, CD7 antikoerper, Cd7 antikoerper
- Hintergrund
- GP40, Leu9, p41, T-cell leukemia antigen, T-cell surface antigen Leu-9, Tp40, TP41
- Molekulargewicht
- 40 kDa
- Gen-ID
- 924, 186820
- UniProt
- P09564
- Pathways
- Cell-Cell Junction Organization
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