EpCAM Antikörper (Extracellular Domain)

Produktnummer ABIN6158700

Produktdetails anti-EpCAM Antikörper

Target: EpCAM (EPCAM) (Epithelial Cell Adhesion Molecule (EPCAM))

Bindungsspezifität: AA 77-202, Extracellular Domain

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser EpCAM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), ELISA, Coating (Coat)

Verwendungszweck: Mouse Monoclonal anti Ep-CAM / CD326 (HEA125)

Produktmerkmale: This antibody recognizes a 40-43 kDa transmembrane epithelial glycoprotein, identified as epithelial specific antigen (ESA), or epithelial cellular adhesion molecule (Ep-CAM). It is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas with the exception of adult squamous epithelium, hepatocytes and gastric epithelial cells. Antibody to Ep-CAM has been used to distinguish adenocarcinoma from pleural mesothelioma and hepatocellular carcinoma. It is also useful in distinguishing serous carcinomas of the ovary from mesothelioma. It has been reported that this epithelial antigen plays an important role as a tumor-cell marker in lymph nodes from patients with esophageal carcinoma otherwise classified as node-negative.

Aufreinigung: Purified

Immunogen: Recombinant human EpCAM protein fragment from the extracellular domain (aa77-202) (exact sequence is proprietary)

Klon: HEA125

Isotyp: IgG2b kappa

Anwendungsinformationen

Applikationshinweise: ELISA 2-4 μg/mL for coating (order Ab without BSA)

• Flow Cytometry 0.5-1 μg/million cells/0.1 mL
• Immunofluorescence 1-2 μg/mL
• Western blotting 0.5-1 μg/mL
• Optimal dilution for a specific application should be determined by user

Kommentare:

HT29 cells or breast tumor

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS (no BSA, no azide)

Konservierungsmittel: Azide free

Details zu EpCAM

Target: EpCAM (EPCAM) (Epithelial Cell Adhesion Molecule (EPCAM))

Andere Bezeichnung: Ep-CAM / CD326 (EPCAM Produkte)

Synonyme: DIAR5 antikoerper, EGP-2 antikoerper, EGP314 antikoerper, EGP40 antikoerper, ESA antikoerper, HNPCC8 antikoerper, KS1/4 antikoerper, KSA antikoerper, M4S1 antikoerper, MIC18 antikoerper, MK-1 antikoerper, TACSTD1 antikoerper, TROP1 antikoerper, ECS-1 antikoerper, ECS1 antikoerper, ESA1 antikoerper, M17S1 antikoerper, EGP antikoerper, Ep-CAM antikoerper, sb:cb6 antikoerper, tacstd antikoerper, wu:fj17g02 antikoerper, zgc:110304 antikoerper, zgc:77119 antikoerper, tacstd1 antikoerper, MGC80540 antikoerper, EPCAM antikoerper, egp antikoerper, ksa antikoerper, m4s1 antikoerper, mk-1 antikoerper, cd326 antikoerper, egp40 antikoerper, mic18 antikoerper, trop1 antikoerper, ep-cam antikoerper, hegp-2 antikoerper, co17-1a antikoerper, ga733-2 antikoerper, CD326 antikoerper, Egp314 antikoerper, EpCAM1 antikoerper, GA733-2 antikoerper, Ly74 antikoerper, Tacsd1 antikoerper, Tacstd1 antikoerper, gp40 antikoerper, epithelial cell adhesion molecule antikoerper, flotillin 2 antikoerper, epithelial cell adhesion molecule S homeolog antikoerper, EPCAM antikoerper, FLOT2 antikoerper, epcam antikoerper, epcam.S antikoerper, Epcam antikoerper

Hintergrund: Adenocarcinoma-associated Antigen| Cell Surface Glycoprotein Trop-1| EGP2| EGP314| EGP40| Epithelial Cell Adhesion Molecule| Epithelial Glycoprotein 314| ESA| KSA| TACD1| TROP1| Tumor-associated Calcium Signal Transducer 1 (TACSTD1)| ECS-1| Epidermal Surface Antigen 1| ESA1| FLOT2| Flotillin-2| Membrane Component| Chromosome 17| Surface Marker-1 (M17S1)| REG-1| Reggie-1| Reggie-2

Molekulargewicht: 40-43 kDa

Gen-ID: 4072, 542050

UniProt: P16422