SELPLG Antikörper (CF®640R)
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- Target Alle SELPLG Antikörper anzeigen
- SELPLG (Selectin P Ligand (SELPLG))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser SELPLG Antikörper ist konjugiert mit CF®640R
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Applikation
- Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunostaining (ISt)
- Verwendungszweck
- Mouse Monoclonal anti-CD162 (PSGL1/1601), CF640R Conjugate
- Produktmerkmale
- CD162 glycoprotein functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Immunogen
- Recombinant human full-length SELPLG (CD162) protein
- Klon
- PSGL1-1601
- Isotyp
- IgG1
- Top Product
- Discover our top product SELPLG Primärantikörper
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- Applikationshinweise
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Immunohistology (formalin) 1-2 μg/mL
- Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM Tris, 1 mM EDTA pH 9.0 for 10-20 min followed by cooling at RT for 20 min
- Immunofluorescence 0.5-1 μg/mL
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Optimal dilution for a specific application should be determined by user
- Kommentare
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Jurkat cells. Tonsil or Spleen
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 100 μg/mL
- Buffer
- PBS/0.1 % BSA/0.05 % azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Protect from light
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- Target
- SELPLG (Selectin P Ligand (SELPLG))
- Andere Bezeichnung
- CD162 (SELPLG Produkte)
- Synonyme
- CD162 antikoerper, CLA antikoerper, PSGL-1 antikoerper, PSGL1 antikoerper, SELPLG antikoerper, SELPG antikoerper, Psgl-1 antikoerper, Psgl1 antikoerper, Selp1 antikoerper, Selpl antikoerper, selectin P ligand antikoerper, selectin, platelet (p-selectin) ligand antikoerper, clasper antikoerper, SELPLG antikoerper, Selplg antikoerper, cla antikoerper
- Hintergrund
- CD162, CLA, Cutaneous lymphocyte associated antigen, P-selectin glycoprotein lig, 1, PSGL1, Selectin P lig, SELPLG
- Molekulargewicht
- 43-120 kDa
- Gen-ID
- 6404, 591014
- UniProt
- Q14242
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