Thrombomodulin Antikörper (AA 69-194) (CF®647)
-
- Target Alle Thrombomodulin (THBD) Antikörper anzeigen
- Thrombomodulin (THBD)
-
Bindungsspezifität
- AA 69-194
-
Reaktivität
- Human
-
Wirt
- Maus
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser Thrombomodulin Antikörper ist konjugiert mit CF®647
-
Applikation
- Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Coating (Coat), Immunostaining (ISt)
- Verwendungszweck
- Mouse Monoclonal anti-Thrombomodulin / CD141 (THBD/1782), CF647 Conjugate
- Produktmerkmale
- This antibody recognizes a protein of 75 kDa, identified as Thrombomodulin. Thrombomodulin is a transmembrane glycoprotein with natural anticoagulant properties. It is normally expressed by a restricted number of cells, such as endothelial and mesothelial cells. In addition, synovial lining and syncytio-trophoblasts of placenta also express thrombomodulin. This protein is present in almost all of benign vascular tumors and majority of malignant vascular tumors (Kaposi s sarcoma, angiosarcoma, and epithelioid hemangioendothelioma). Hence, anti-thrombomodulin serves as a sensitive marker for lymphatic endothelial cells and their tumors. Recently, thrombomodulin antibody has been used for mesothelial cells and malignant mesotheliomas. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Immunogen
- Recombinant human Thrombomodulin protein fragment (aa69-194) (exact sequence is proprietary)
- Klon
- THBD-1782
- Isotyp
- IgG2a kappa
- Top Product
- Discover our top product THBD Primärantikörper
-
-
- Applikationshinweise
-
Immunohistology (formalin) 1-2 μg/mL
- ELISA 2-4 μg/mL for coating (order Ab without BSA)
- Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM Tris buffer with1 mM EDTA pH 9.0 for 10-20 min followed by cooling at RT for 20 min
- Immunofluorescence 0.5-1 μg/mL
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Optimal dilution for a specific application should be determined by user
- Kommentare
-
THP1 Cells. Placenta, Angiosarcoma, Bladder or Cervical Carcinoma
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 100 μg/mL
- Buffer
- PBS/0.1 % BSA/0.05 % azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Protect from light
-
- Target
- Thrombomodulin (THBD)
- Andere Bezeichnung
- Thrombomodulin / CD141 (THBD Produkte)
- Synonyme
- AHUS6 antikoerper, BDCA3 antikoerper, CD141 antikoerper, THPH12 antikoerper, THRM antikoerper, TM antikoerper, AI385582 antikoerper, THBD antikoerper, HAST antikoerper, HAST3 antikoerper, M-PST antikoerper, ST1A3/ST1A4 antikoerper, ST1A5 antikoerper, STM antikoerper, TL-PST antikoerper, thrombomodulin antikoerper, sulfotransferase family 1A member 3 antikoerper, THBD antikoerper, Thbd antikoerper, SULT1A3 antikoerper
- Hintergrund
- AHUS6, BDCA3, CD141, Fetomodulin, Thbd, THPH12, THRM, Thrombomodulin (TM)
- Molekulargewicht
- 100 kDa
- Gen-ID
- 7056, 2030
- UniProt
- P07204
-