VWF Antikörper (AA 1815-1939) (Biotin)
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- Target Alle VWF Antikörper anzeigen
- VWF (Von Willebrand Factor (VWF))
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Bindungsspezifität
- AA 1815-1939
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser VWF Antikörper ist konjugiert mit Biotin
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunofluorescence (IF)
- Verwendungszweck
- Mouse Monoclonal anti-von-Willebrand Factor / Factor-VIII-Related Ag (VWF/1465), Biotin Conjugate
- Produktmerkmale
- von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposi s sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Immunogen
- Recombinant fragment of human vWF protein (aa1815-1939) (exact sequence is proprietary)
- Klon
- VWF-1465
- Isotyp
- IgG1
- Top Product
- Discover our top product VWF Primärantikörper
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- Applikationshinweise
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Immunohistology (formalin) 1-2 μg/mL
- Western blotting 0.5-1 μg/mL Immunoprecipitation 0.5-1 μg/500 μg protein lysate
- Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min
- Immunofluorescence 0.5-1 μg/mL
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Optimal dilution for a specific application should be determined by user
- Kommentare
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HUVEC cells or Tonsil
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 100 μg/mL
- Buffer
- PBS/0.1 % BSA/0.05 % azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- Target
- VWF (Von Willebrand Factor (VWF))
- Andere Bezeichnung
- von-Willebrand Factor / Factor-VIII-Related Ag (VWF Produkte)
- Synonyme
- VWF antikoerper, si:ch1073-474e24.1 antikoerper, F8VWF antikoerper, VWD antikoerper, 6820430P06Rik antikoerper, AI551257 antikoerper, B130011O06Rik antikoerper, C630030D09 antikoerper, von Willebrand factor antikoerper, Von Willebrand factor antikoerper, VWF antikoerper, vwf antikoerper, Vwf antikoerper
- Hintergrund
- Coagulation Factor VIII, Factor VIII Related Antigen, F8VWF, von Willebr, Antigen 2, von Willebr, Disease (vWD)
- Molekulargewicht
- 250 kDa
- Gen-ID
- 7450, 440848
- UniProt
- P04275
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