MCAM Antikörper (CF®488A)
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- Target Alle MCAM Antikörper anzeigen
- MCAM (Melanoma Cell Adhesion Molecule (MCAM))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser MCAM Antikörper ist konjugiert mit CF®488A
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Applikation
- Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Verwendungszweck
- Mouse Monoclonal anti-MUC18 / Mucin 18 / CD146 (MUC18/1130), CF488A Conjugate
- Produktmerkmale
- The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2 -independent cell adhesion molecule. Mel-CAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. Mel-CAM is found on 80 % of advanced primary human melanomas and correlates well with development of metastatic disease. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Immunogen
- Recombinant human MUC18 protein
- Klon
- MUC18-1130
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product MCAM Primärantikörper
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- Applikationshinweise
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Immunohistology (formalin)
- Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Immunofluorescence 0.5-1.0 μg/mL
- Optimal dilution for a specific application should be determined by user
- Kommentare
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A-375, HUV-EC or HeLa Cells. Tonsil or Melanoma.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 100 μg/mL
- Buffer
- PBS/0.1 % BSA/0.05 % azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Protect from light
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- Target
- MCAM (Melanoma Cell Adhesion Molecule (MCAM))
- Andere Bezeichnung
- MUC18 / Mucin 18 / CD146 (MCAM Produkte)
- Synonyme
- CD146 antikoerper, MUC18 antikoerper, Muc18 antikoerper, 1-gicerin antikoerper, AV025631 antikoerper, CD149 antikoerper, s-endo antikoerper, s-gicerin antikoerper, cd146 antikoerper, gicerin antikoerper, id:ibd3512 antikoerper, mcam antikoerper, MCAM antikoerper, melanoma cell adhesion molecule antikoerper, melanoma cell adhesion molecule b antikoerper, MCAM antikoerper, Mcam antikoerper, mcamb antikoerper
- Molekulargewicht
- 130 kDa
- Gen-ID
- 4162, 599039
- UniProt
- P43121
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