TNNI2 Antikörper (AA 1-100)

Produktnummer ABIN6149355

Produktdetails anti-TNNI2 Antikörper

Target: TNNI2 (Fast Skeletal Troponin I (TNNI2))

Bindungsspezifität: AA 1-100

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TNNI2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MGDEEKRNRA ITARRQHLKS VMLQIAATEL EKEESRREAE KQNYLAEHCP PLHIPGSMSE VQELCKQLHA KIDAAEEEKY DMEVRVQKTS KELEDMNQKL

Kreuzreaktivität: Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human Troponin I2 (Troponin I2 (TNNI2)) (NP_003273.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-TNNI2 Antikörper (ABIN6149355)

Fan, Long, Yan, Wang, Shi, Bao, Hu, Li, Chen, Zheng, Yan: "Dietary leucine supplementation alters energy metabolism and induces slow-to-fast transitions in longissimus dorsi muscle of weanling piglets." in: The British journal of nutrition, Vol. 117, Issue 9, pp. 1222-1234, (2017) (PubMed).

Details zu TNNI2

Target: TNNI2 (Fast Skeletal Troponin I (TNNI2))

Andere Bezeichnung: TNNI2 (TNNI2 Produkte)

Synonyme: AMCD2B antikoerper, DA2B antikoerper, FSSV antikoerper, fsTnI antikoerper, TnI-F4 antikoerper, TnI antikoerper, TNI antikoerper, hm:zehn0173 antikoerper, tnni2 antikoerper, tropI-1d antikoerper, zgc:86800 antikoerper, troponin I2, fast skeletal type antikoerper, troponin I type 2 (skeletal, fast) antikoerper, troponin I, fast skeletal muscle-like antikoerper, troponin I, skeletal, fast 2 antikoerper, troponin I type 2a (skeletal, fast), tandem duplicate 4 antikoerper, TNNI2 antikoerper, Tnni2 antikoerper, tnni2a.4 antikoerper

Hintergrund: This gene encodes a fast-twitch skeletal muscle protein, a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, along with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. Mouse studies show that this component is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function. In addition to muscle tissues, this protein is found in corneal epithelium, cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis, and mammary gland where it functions as a co-activator of estrogen receptor-related receptor alpha. This protein also suppresses tumor growth in human ovarian carcinoma. Mutations in this gene cause myopathy and distal arthrogryposis type 2B. Alternatively spliced transcript variants have been found for this gene.,TNNI2,AMCD2B,DA2B,FSSV,fsTnI,troponin I2,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,TNNI2

Molekulargewicht: 21 kDa

Gen-ID: 7136

UniProt: P48788