TGS1 Antikörper (AA 714-853)

Produktnummer ABIN6149101

Produktdetails anti-TGS1 Antikörper

Target: TGS1 (Trimethylguanosine Synthase 1 (TGS1))

Bindungsspezifität: AA 714-853

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TGS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: RVIAIDIDPV KIALARNNAE VYGIADKIEF ICGDFLLLAS FLKADVVFLS PPWGGPDYAT AETFDIRTMM SPDGFEIFRL SKKITNNIVY FLPRNADIDQ VASLAGPGGQ VEIEQNFLNN KLKTITAYFG DLIRRPASET

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 714-853 of human TGS1 (NP_079107.6).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu TGS1

Target: TGS1 (Trimethylguanosine Synthase 1 (TGS1))

Andere Bezeichnung: TGS1 (TGS1 Produkte)

Synonyme: NCOA6IP antikoerper, PIMT antikoerper, PIPMT antikoerper, D4Ertd800e antikoerper, Ncoa6ip antikoerper, Pimt antikoerper, trimethylguanosine synthase 1 antikoerper, trimethylguanosine synthase 1 L homeolog antikoerper, TGS1 antikoerper, Tgs1 antikoerper, tgs1.L antikoerper

Hintergrund: Catalyzes the 2 serial methylation steps for the conversion of the 7-monomethylguanosine (m(7G caps of snRNAs and snoRNAs to a 2,2,7-trimethylguanosine (m(2,2,7G cap structure. The enzyme is specific for guanine, and N7 methylation must precede N2 methylation. Hypermethylation of the m7G cap of U snRNAs leads to their concentration in nuclear foci, their colocalization with coilin and the formation of canonical Cajal bodies (CBs. Plays a role in transcriptional regulation.,TGS1,NCOA6IP,PIMT,PIPMT,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Nuclear hormone receptors,Cancer,Signal Transduction,TGS1

Molekulargewicht: 96 kDa

Gen-ID: 96764

UniProt: Q96RS0

Pathways: Mitotic G1-G1/S Phases, Regulation of Lipid Metabolism by PPARalpha, Ribonucleoprotein Complex Subunit Organization