SPSB1 Antikörper (AA 1-60)

Produktnummer ABIN6148398

Produktdetails anti-SPSB1 Antikörper

Target: SPSB1 (SplA/ryanodine Receptor Domain and SOCS Box Containing 1 (SPSB1))

Bindungsspezifität: AA 1-60

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPSB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MGQKVTGGIK TVDMRDPTYR PLKQELQGLD YCKPTRLDLL LDMPPVSYDV QLLHSWNNND

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-60 of human SPSB1 (NP_079382.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu SPSB1

Target: SPSB1 (SplA/ryanodine Receptor Domain and SOCS Box Containing 1 (SPSB1))

Andere Bezeichnung: SPSB1 (SPSB1 Produkte)

Synonyme: SSB-1 antikoerper, SSB1 antikoerper, 1110014L01Rik antikoerper, 4930422J18Rik antikoerper, AI596360 antikoerper, AI854583 antikoerper, splA/ryanodine receptor domain and SOCS box containing 1 antikoerper, SPSB1 antikoerper, Spsb1 antikoerper

Hintergrund: Substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Negatively regulates nitric oxide (NO production and limits cellular toxicity in activated macrophages by mediating the ubiquitination and proteasomal degradation of NOS2. Acts as a bridge which links NOS2 with the ECS E3 ubiquitin ligase complex components ELOC and CUL5.,SPSB1,SSB-1,SSB1,SPSB1

Molekulargewicht: 30 kDa

Gen-ID: 80176

UniProt: Q96BD6