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CD34 Antikörper

CD34 Reaktivität: Human, Primate FACS, WB, IP, IHC (fro), Func Wirt: Maus Monoclonal QBEnd-10 unconjugated
Produktnummer ABIN614812
  • Target Alle CD34 Antikörper anzeigen
    CD34
    Reaktivität
    • 311
    • 115
    • 105
    • 33
    • 19
    • 18
    • 17
    • 17
    • 16
    • 16
    • 9
    • 6
    • 5
    • 1
    • 1
    Human, Primate
    Wirt
    • 181
    • 145
    • 22
    • 6
    • 4
    Maus
    Klonalität
    • 239
    • 116
    • 2
    Monoklonal
    Konjugat
    • 130
    • 29
    • 28
    • 23
    • 18
    • 8
    • 8
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD34 Antikörper ist unkonjugiert
    Applikation
    • 241
    • 206
    • 92
    • 67
    • 62
    • 53
    • 39
    • 37
    • 33
    • 28
    • 23
    • 20
    • 13
    • 7
    • 7
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)
    Spezifität
    This antibody reacts with Class II epitope on CD34 (Mucosialin), a 110-115 kDa monomeric transmembrane phosphoglycoprotein expressed on hematopoietic progenitors cells and on the most pluripotential stem cells, it is gradually lost on progenitor cells. This antibody has been also used as an endothelial marker.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human, Non-Human Primates, negative on Rat, Bovine, Sheep, Canine (Dog)
    Aufreinigung
    Protein-A affinity chromatography
    Reinheit
    > 95 % pure by SDS-PAGE
    Immunogen
    Human endothelial vesicles
    Klon
    QBEnd-10
    Isotyp
    IgG1
    Top Product
    Discover our top product CD34 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    Azide free phosphate buffered saline (PBS), approx. pH 7.4, 0.2 μm filter sterilized
    Konservierungsmittel
    Azide free
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target
    CD34
    Andere Bezeichnung
    CD34 (CD34 Produkte)
    Synonyme
    AU040960 antikoerper, CD34 molecule antikoerper, CD34 antigen antikoerper, CD34 antikoerper, Cd34 antikoerper
    Hintergrund
    CD34 is a highly glycosylated monomeric 111-115 kDa surface protein, which is present on many stem cell populations. It is a well established stem cell marker, though its expression on human hematopoietic stem cells is reversible. CD34 probably serves as a surface receptor that undergoes receptor-mediated endocytosis and regulates adhesion, differentiation and proliferation of hematopoietic stem cells and other progenitors. CD34 expression is likely to represent a specific state of hematopoietic development that may have altered adhering properties with expanding and differentiating capabilities in both in vitro and in vivo conditions.Synonyms: Hematopoietic progenitor cell antigen CD34, Hematopoietic progenitor cell marker
    Gen-ID
    947
    NCBI Accession
    NP_001020280
    UniProt
    P28906
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