Maus anti-Human IgG (Fc Region) Antikörper

Details zu Produkt Nr. ABIN614786, Anbieter: Anmelden zum Anzeigen
Antigen
Epitop
Fc Region
6300
1954
1757
1065
889
727
375
301
35
34
31
15
11
7
3
3
1
1
1
1
1
1
1
Reaktivität
Human
3070
2883
2372
1625
1469
784
689
459
454
396
364
362
301
288
279
146
128
114
42
34
29
26
16
15
11
10
8
7
5
5
4
4
3
3
3
3
3
3
3
2
2
2
1
1
1
1
1
1
1
Wirt
Maus
6986
5079
1920
1048
523
358
89
84
55
35
23
15
8
5
3
1
1
Klonalität (Klon)
Monoklonal ()
Applikation
Immunofluorescence (IF)
Optionen
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Hersteller Produkt- Nr.
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Immunogen Fusion protein of human IgG Fc fragment
Klon EM-07
Isotyp IgG1
Kreuzreaktivität (Details) Species reactivity (tested):Human.
Reinigung Protein A affinity Chromatography
Reinheit > 95 % pure by SDS-PAGE
Antigen
Hintergrund Immunoglobulin G (IgG) is a 150 kDa soluble protein that serves as a major effector molecule of the humoral immune response in man. Its concentration in blood plasma of healthy individuals is approximately 10 g/l, which accounts for about 75 % of the total plasma immunoglobulins. IgG has the highest stability of blood immunoglobulins (T1/2 = 21 days) and is able of placental transfer. IgG is secreted by plasma cells at a comparably high rate as other immunoglobulins.Synonyms: Human Immunoglobulin G
Molekulargewicht 150 kDa
Applikations-hinweise Optimal working dilutions should be determined experimentally by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1.0 mg/mL
Buffer PBS, pH ~7.4, 15 mM Sodium Azide
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
Bilder des Herstellers
Western Blotting (WB) image for Mouse anti-Human IgG (Fc Region) antibody (ABIN614786) Mouse anti-Human IgG (Fc Region) antibody
Allgemeine Veröffentlichungen Brinkmann, Heusser: "T cell-dependent differentiation of human B cells into IgM, IgG, IgA, or IgE plasma cells: high rate of antibody production by IgE plasma cells, but limited clonal expansion of IgE precursors." in: Cellular immunology, Vol. 152, Issue 2, pp. 323-32, 1994 (PubMed).

Balogh, Merétey, Falus, Bozsóky: "Serological abnormalities in juvenile chronic arthritis: a review of 46 cases." in: Annals of the rheumatic diseases, Vol. 39, Issue 2, pp. 129-34, 1980 (PubMed).

Fuller, Keyser: "Serum immunoglobulins after surgical operation." in: Clinical chemistry, Vol. 21, Issue 6, pp. 667-71, 1975 (PubMed).

Franklin: "Structure and function of immunoglobulins." in: Acta endocrinologica. Supplementum, Vol. 194, pp. 77-95, 1975 (PubMed).