OCT4 Antikörper
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- Target Alle OCT4 (POU5F1) Antikörper anzeigen
- OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser OCT4 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Kreuzreaktivität
- Human, Maus, Ratte
- Produktmerkmale
- Polyclonal Antibodies
- Immunogen
- A synthetic peptide of human OCT4
- Isotyp
- IgG
- Top Product
- Discover our top product POU5F1 Primärantikörper
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- Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
- Kommentare
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HIGH QUALITY
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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NSPc1 promotes cancer stem cell self-renewal by repressing the synthesis of all-trans retinoic acid via targeting RDH16 in malignant glioma." in: Oncogene, Vol. 36, Issue 33, pp. 4706-4718, (2017) (PubMed).
: "NOR1 Suppresses Cancer Stem-Like Cells Properties of Tumor Cells via the Inhibition of the AKT-GSK-3β-Wnt/β-catenin-ALDH1A1 Signal Circuit." in: Journal of cellular physiology, Vol. 232, Issue 10, pp. 2829-2840, (2017) (PubMed).
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NSPc1 promotes cancer stem cell self-renewal by repressing the synthesis of all-trans retinoic acid via targeting RDH16 in malignant glioma." in: Oncogene, Vol. 36, Issue 33, pp. 4706-4718, (2017) (PubMed).
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- Target
- OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))
- Andere Bezeichnung
- POU5F1 (POU5F1 Produkte)
- Synonyme
- OCT3 antikoerper, OCT4 antikoerper, OTF-3 antikoerper, OTF3 antikoerper, OTF4 antikoerper, Oct-3 antikoerper, Oct-4 antikoerper, POU5F1 antikoerper, gp9 antikoerper, gp-9 antikoerper, oct4 antikoerper, pou2 antikoerper, POU-2 antikoerper, cb197 antikoerper, spg/pou2 antikoerper, chunp6868 antikoerper, wu:fd18d06 antikoerper, NF-A3 antikoerper, Oct-3/4 antikoerper, Oct3 antikoerper, Oct3/4 antikoerper, Oct4 antikoerper, Otf-3 antikoerper, Otf-4 antikoerper, Otf3 antikoerper, Otf3-rs7 antikoerper, Otf3g antikoerper, Otf4 antikoerper, POU class 5 homeobox 1 antikoerper, POU domain, class 5, transcription factor 3 antikoerper, POU domain, class 5, transcription factor 1 antikoerper, POU5F1 antikoerper, pou5f3 antikoerper, Pou5f1 antikoerper
- Hintergrund
- This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12.,POU5F1,OCT3,OCT4,OTF-3,OTF3,OTF4,Oct-3,Oct-4,Epigenetics & Nuclear Signaling,Transcription Factors,RNA Binding,Cell Biology & Developmental Biology,ESC Pluripotency and Differentiation,Stem Cells,Embryonic Stem Cells,Germline Stem Cells,POU5F1
- Molekulargewicht
- 30 kDa/38 kDa
- Gen-ID
- 5460
- UniProt
- Q01860
- Pathways
- Stem Cell Maintenance
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